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CAS 84687-43-4

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Astragaloside IV

Description:
Astragaloside IV is a natural compound primarily derived from the root of Astragalus membranaceus, a traditional medicinal herb. It belongs to the class of saponins, which are glycosides with a steroid or triterpenoid aglycone. This compound is known for its potential pharmacological properties, including immunomodulatory, anti-inflammatory, and antioxidant effects. Astragaloside IV has been studied for its ability to enhance immune function and protect against oxidative stress, making it of interest in various therapeutic applications. The substance is typically characterized by its solubility in water and organic solvents, and it exhibits a relatively low toxicity profile. Its molecular structure features a sugar moiety attached to a triterpenoid backbone, which contributes to its biological activity. Research continues to explore its mechanisms of action and potential benefits in health and disease management, particularly in the context of chronic conditions and aging.
Formula:C41H68O14
InChI:InChI=1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1
InChI key:InChIKey=QMNWISYXSJWHRY-YLNUDOOFSA-N
SMILES:C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C3)(C(C)(C)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O)CO7)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@]8(C)O[C@H](C(C)(C)O)CC8)[H])[H]
Synonyms:
  • (3β,6α,16β,20R,24S)-20,24-Epoxy-16,25-dihydroxy-3-(β-<span class="text-smallcaps">D</smallcap>-xylopyranosyloxy)-9,19-cyclolanostan-6-yl β-<smallcap>D</span>-glucopyranoside
  • (5xi,6beta,8xi,9xi,16alpha,20R,24S)-16,25-dihydroxy-3-(beta-D-xylopyranosyloxy)-20,24-epoxy-9,19-cyclolanostan-6-yl beta-D-glucopyranoside
  • 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
  • 9,19-Cyclolanostane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
  • Astrasieversianin XIV
  • Astraversianin XIV
  • Cyclosieversioside F
  • Cyclosiversioside F
  • astragalosideⅣ
  • beta-D-Glucopyranoside, (3beta,6alpha,16beta,20R,24S)-20,24-epoxy-16,25-dihydroxy-3-(beta-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl
  • See more synonyms
Found 16 products.
  • Astragaloside IV

    CAS:
    Formula:C41H68O14
    Purity:>98.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:784.98

    Ref: 3B-A3305

    250mg
    107.00€
    1g
    308.00€
  • ASTRAGALOSIDE IV CRS

    CAS:
    ASTRAGALOSIDE IV CRS
    Formula:C41H68O14
    Molecular weight:784.9702

    Ref: 41-Y0001171

    40mg
    132.00€
  • Astragaloside IV

    CAS:
    Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi
    Formula:C41H68O14
    Color and Shape:Off-White Powder
    Molecular weight:784.46091
  • Astragaloside IV

    CAS:
    Astragaloside IV
    Formula:C41H68O14
    Purity:99.5%
    Molecular weight:784.97

    Ref: 54-BUP16973

    5mg
    51.00€
    10mg
    83.00€
    25mg
    117.00€
    50mg
    183.00€
    100mg
    293.00€
    500mg
    657.00€
  • Astragaloside IV

    CAS:
    Formula:C41H68O14
    Color and Shape:White To Off-White Solid
    Molecular weight:784.98

    Ref: 4Z-A-326001

    5mg
    To inquire
    100mg
    To inquire
    10mg
    436.00€
    25mg
    623.00€
    50mg
    810.00€
  • Astragaloside IV

    CAS:
    Astragaloside IV
    Formula:C41H68O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:784.97

    Ref: 54-OR1030333

    250mg
    30.00€
    1g
    51.00€
    5g
    180.00€
    25g
    738.00€
    100g
    1,912.00€
  • Astragaloside IV

    CAS:
    Formula:C41H68O14
    Purity:≥ 98.0%
    Color and Shape:White to off-white powder
    Molecular weight:784.97

    Ref: 7W-GL0129

    1mg
    104.00€
    5mg
    306.00€
  • Astragaloside IV (Standard)

    CAS:
    Astragaloside IV (Standard) is a reference standard for research and analysis in studies involving Astragaloside IV. Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 μM; LC50 = 865 μM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.
    Formula:C41H68O14
    Molecular weight:784.97
  • Astragaloside IV

    CAS:
    Astragaloside IV, a saponin isolated from Astragalus membranaceus, has been shown to protect the myocardium against ischemia/reperfusion injury, it also has beneficial effect in H/R-induced injury may be related to normalization of SR Ca2+ pump expression and, thus, it may prevent the depression in SR Ca2+ handling.
    Formula:C41H68O14
    Purity:95%~99%
    Color and Shape:White powder
    Molecular weight:784.981

    Ref: BP-BP0213

    20mg
    53.00€
  • Astragaloside IV

    Controlled Product
    CAS:

    Applications Astragaloside IV has cardiovascular protective effects, protecting the vascular endothelial cells. In addition it is attributed to have anti0inflammatory and anti-virus effects as well. This is due to its scavenging ability of oxygen free radicals, regulation of mineral homeostasis and antioxidative effects.
    References Liu, S. et al.: J. Chinese Pharm. Sci., 22, 222 (2013);

    Formula:C41H68O14
    Color and Shape:Neat
    Molecular weight:784.97

    Ref: TR-A790130

    5mg
    169.00€
    10mg
    295.00€
  • Astragaloside IV

    CAS:
    Astragaloside IV suppresses ERK1/2, JNK, MMP-2/9 in breast cancer; inhibits adenovirus and protects cardiovascular, immune, digestive, nervous systems.
    Formula:C41H68O14
    Purity:99% - 99.84%
    Color and Shape:Solid
    Molecular weight:784.9702
  • Astragaloside IV

    CAS:
    Natural glycoside
    Formula:C41H68O14
    Purity:≥ 90.0 % (HPLC)
    Color and Shape:Powder
    Molecular weight:784.99

    Ref: 5G-89377

    10mg
    345.00€
    50mg
    1,404.00€
    250mg
    6,627.00€
    500mg
    12,474.00€
    1000mg
    23,389.00€
  • Astragaloside IV

    CAS:
    Formula:C41H68O14
    Molecular weight:785.0

    Ref: BE-RMT12370

    25mg
    69.00€
  • Astragaloside IV

    CAS:
    Formula:C41H68O14
    Molecular weight:785.0

    Ref: BE-RMCA305000

    5mg
    48.00€
  • Astragaloside IV

    CAS:
    (2R,3R,4S,5S,6R)-2-(((2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-4-Hydroxy-3-((2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyl-9-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetradecahydro-1H,12H-cyclopenta[a]cyclopropa[e]phenanthren-7-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
    Formula:C41H68O14
    Purity:98%
    Molecular weight:784.97
  • Astragaloside IV

    CAS:
    Astragaloside IV is a bioactive compound, which is a primary saponin derived from the roots of Astragalus membranaceus, a plant commonly used in traditional Chinese medicine. This compound functions primarily through modulating cellular signaling pathways, exhibiting its effects via antioxidant, anti-inflammatory, and immunomodulatory actions.
    Formula:C41H68O14
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:784.97 g/mol

    Ref: 3D-MA08288

    2g
    Discontinued
    500mg
    Discontinued
    1g
    Discontinued
    5g
    Discontinued
    10g
    Discontinued
    Discontinued product