CAS 847862-26-4

tert-Butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

CAS: 847862-26-4

Formula: C₁₂H₂₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 226.3153

Ref: IN-DA00G80B

tert-Butyl (8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

CAS: 847862-26-4

tert-Butyl (8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

Purity: 97%

Ref: 54-OR1041732

tert-butyl (8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

CAS: 847862-26-4

Formula: C₁₂H₂₂N₂O₂

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 226.168

Ref: 10-F385737

Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate

CAS: 847862-26-4

Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate (tBAA) is a heterocycle that has been modified to enhance its pharmacokinetic properties. Tert-butyl(8-anti)-3-azabicyclo[3.2.1]oct-8-ylcarbamate was designed to be metabolically stable and have a high bioavailability and isosteric properties with phosphatidylinositol, which it uses as a substrate in the catalytic cycle. This modification also increased tBAA's stability in vivo, leading to an increase in efficacy. The covalent attachment of the phenyl ring on the tertiary amine nitrogen of tBAA provides additional protection against hepatic metabolism by CYP450 enzymes, making it more potent than other compounds with similar structures that are not covalently attached to the amine group.

Formula: C₁₂H₂₂N₂O₂

Purity: Min. 95%

Molecular weight: 226.32 g/mol

Ref: 3D-FT167890