CAS 847949-50-2

2-Chloro-4-[[7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenol

Description:

2-Chloro-4-[[7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenol, with CAS number 847949-50-2, is a synthetic organic compound characterized by its complex molecular structure, which includes a chloro group, a phenolic hydroxyl group, and a quinazoline moiety. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity due to its structural features, which may interact with biological targets. The presence of the morpholine ring suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. Its molecular design indicates possible roles in inhibiting specific enzymes or receptors, making it a candidate for further research in therapeutic contexts. Additionally, the methoxy and propoxy substituents may influence its pharmacokinetic properties, including absorption and distribution. As with many compounds of this nature, safety and handling precautions are essential, given the potential for biological activity and the presence of chlorine in its structure.

Formula: C₂₂H₂₅ClN₄O₄

InChI: InChI=1S/C22H25ClN4O4/c1-29-20-13-18-16(12-21(20)31-8-2-5-27-6-9-30-10-7-27)22(25-14-24-18)26-15-3-4-19(28)17(23)11-15/h3-4,11-14,28H,2,5-10H2,1H3,(H,24,25,26)

InChI key: InChIKey=IQWXTDMHBQBADK-UHFFFAOYSA-N

SMILES: N(C=1C2=C(C=C(OC)C(OCCCN3CCOCC3)=C2)N=CN1)C4=CC(Cl)=C(O)C=C4

Synonyms:

• 2-Chloro-4-[[7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenol
• Phenol, 2-chloro-4-[[7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]-
• 4-Desfluoro 4-Hydroxy Gefitinib metabolite
• Gefitinib impurity 15/4-Defluoro-4-Hydroxy Gefitinib/2-chloro-4-((7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)amino)phenol
• 4-Defluoro-4-hydroxy Gefitinib
• Gefitinib iMpurity B
• Gefitinib 4-Desfluoro 4-Hydroxy
• 2-chloro-4-((7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)amino)phenol
• 2-chloro-4-[[7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenol

4-Defluoro-4-Hydroxy Gefitinib

CAS: 847949-50-2

Formula: C₂₂H₂₅ClN₄O₄

Color and Shape: Gray Solid

Molecular weight: 444.92

Ref: 4Z-G-236

4-Defluoro-4-hydroxy Gefitinib

Controlled Product

CAS: 847949-50-2

Applications A metabolite of Gefitinib (G304000).
References Newton, D., et al.: Drug Metab. Dispos., 23, 154 (1995), Wakeling, A., et al.: Cancer Res., 62, 5749 (2002), McKillop, D., et al.: Xenobiotica, 34, 917 (2004),

Formula: C₂₂H₂₅ClN₄O₄

Color and Shape: Neat

Molecular weight: 444.91

Ref: TR-D229015

4-Defluoro-4-Hydroxy Gefitinib

CAS: 847949-50-2

Formula: C₂₂H₂₅ClN₄O₄

Molecular weight: 444.92

Ref: ST-EA-CP-G14011