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CAS 848141-11-7

:

Alvelestat

Description:
Alvelestat, with the CAS number 848141-11-7, is a small molecule inhibitor primarily designed to target neutrophil elastase, an enzyme implicated in various inflammatory conditions, particularly in chronic obstructive pulmonary disease (COPD) and other respiratory disorders. This compound is characterized by its ability to modulate inflammatory responses by inhibiting the activity of neutrophil elastase, thereby potentially reducing tissue damage and inflammation associated with excessive neutrophil activity. Alvelestat has been investigated in clinical trials for its therapeutic efficacy and safety profile. Its chemical structure features specific functional groups that contribute to its biological activity and pharmacokinetic properties. As a therapeutic agent, it is important to consider its solubility, stability, and metabolic pathways, which influence its effectiveness and dosing regimen. Overall, Alvelestat represents a promising approach in the management of diseases characterized by neutrophil-mediated inflammation.
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Found 4 products.
  • 6-Methyl-5-(1-Methyl-1H-Pyrazol-5-Yl)-N-((5-(Methylsulfonyl)Pyridin-2-Yl)Methyl)-2-Oxo-1-(3-(Trifl…
    Apollo Scientific
    + Info

    6-Methyl-5-(1-Methyl-1H-Pyrazol-5-Yl)-N-((5-(Methylsulfonyl)Pyridin-2-Yl)Methyl)-2-Oxo-1-(3-(Trifluoromethyl)Phenyl)-1,2-Dihydropyridine-3-Carboxamide

    CAS:
    6-Methyl-5-(1-Methyl-1H-Pyrazol-5-Yl)-N-((5-(Methylsulfonyl)Pyridin-2-Yl)Methyl)-2-Oxo-1-(3-(Trifluoromethyl)Phenyl)-1,2-Dihydropyridine-3-Carboxamide
    Purity:99%+
    Molecular weight:545.53g/mol

    Ref: 54-PC108699

    1g
    1,082.00€
    50mg
    To inquire
    100mg
    250.00€
    250mg
    415.00€
  • Alvelestat
    Apollo Scientific
    + Info

    Alvelestat

    CAS:
    Alvelestat
    Purity:≥98%
    Molecular weight:545.53g/mol

    Ref: 54-BUP08129

    5mg
    85.00€
    10mg
    124.00€
    25mg
    228.00€
    50mg
    334.00€
    100mg
    506.00€
    500mg
    1,186.00€
  • Alvelestat
    Targetmol
    + Info

    Alvelestat

    CAS:
    <p>Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.</p>
    Formula:C25H22F3N5O4S
    Purity:98% - >99.99%
    Color and Shape:Solid
    Molecular weight:545.53

    Ref: TM-T3107

  • Avelestat
    TRC
    + Info

    Avelestat

    Controlled Product
    CAS:
    <p>Applications Avelstat inhibits plasma neutrophil elastase (NE) activity in zymosan-stimulated whole blood, and also inhibits NE activity on the surface of stimulated polymorphonuclear cells and in the supernatant of primed, stimulated cells.<br>References Stevens, T., et al.: J. Pharmacol. Exp. Ther., 339, 313 (2011)<br></p>
    Formula:C25H22F3N5O4S
    Color and Shape:Neat
    Molecular weight:545.53

    Ref: TR-A794660

    5mg
    227.00€
    50mg
    1,086.00€