CAS 848217-00-5

8-chloro-2-methyl-4-(4-methylpiperazin-1-yl)-[1]benzofuro[3,2-d]pyrimidine

Description:

8-Chloro-2-methyl-4-(4-methylpiperazin-1-yl)-[1]benzofuro[3,2-d]pyrimidine is a synthetic organic compound characterized by its complex structure, which includes a benzofuro-pyrimidine core. This compound features a chloro group and a methyl group at specific positions on the pyrimidine ring, as well as a piperazine moiety that contributes to its pharmacological properties. The presence of the chloro substituent typically enhances the compound's lipophilicity, potentially influencing its bioavailability and interaction with biological targets. The piperazine ring is known for its role in enhancing the binding affinity to various receptors, making this compound of interest in medicinal chemistry, particularly in the development of pharmaceuticals. Its unique structural features may confer specific biological activities, which could be explored in therapeutic contexts. As with many synthetic compounds, its stability, solubility, and reactivity are influenced by the functional groups present, and it may exhibit specific interactions with enzymes or receptors in biological systems.

Formula: C₁₆H₁₇ClN₄O

InChI: InChI=1S/C16H17ClN4O/c1-10-18-14-12-9-11(17)3-4-13(12)22-15(14)16(19-10)21-7-5-20(2)6-8-21/h3-4,9H,5-8H2,1-2H3

InChI key: GUJLUPNSRRNJKP-UHFFFAOYSA-N

SMILES: CC1=NC2=C(C(=N1)N3CCN(CC3)C)OC4=C2C=C(C=C4)Cl

Synonyms:

• Benzofuro[3,2-d]pyrimidine, 8-chloro-2-methyl-4-(4-methyl-1-piperazinyl)-
• 8-chloro-2-methyl-4-(4-methylpiperazin-1-yl)-[1]benzofuro[3,2-d]pyrimidine
• H4 Receptor antagonist 1

H4 Receptor antagonist 1

CAS: 848217-00-5

H4 Receptor antagonist 1

Formula: C₁₆H₁₇ClN₄O

Purity: 98.5%

Molecular weight: 316.79

Ref: 54-BUP10059

H4 Receptor antagonist 1

CAS: 848217-00-5

Formula: C₁₆H₁₇ClN₄O

Molecular weight: 316.7854

Ref: IN-DA01FHH8

H4 Receptor antagonist 1

CAS: 848217-00-5

H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.

Formula: C₁₆H₁₇ClN₄O

Purity: 98.81%

Color and Shape: Solid

Molecular weight: 316.785

Ref: TM-T5829