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CAS 84889-09-8

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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-L-phenylalanine

Description:
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-L-phenylalanine, commonly referred to as Fmoc-L-Phe-L-Phe, is a synthetic compound primarily used in peptide synthesis and research. It features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under acidic conditions. The compound consists of two phenylalanine residues, which contribute to its hydrophobic characteristics and potential interactions in biological systems. Its molecular structure includes aromatic rings, which can enhance π-π stacking interactions, making it relevant in studies of protein folding and stability. The presence of the Fmoc group allows for selective protection of the amino group, facilitating the stepwise assembly of peptides. This compound is typically handled under standard laboratory conditions, and its applications extend to drug development, biochemistry, and materials science, where understanding peptide interactions is crucial. As with all chemical substances, proper safety protocols should be followed when handling this compound.
Formula:C33H30N2O5
InChI:InChI=1S/C33H30N2O5/c36-31(34-30(32(37)38)20-23-13-5-2-6-14-23)29(19-22-11-3-1-4-12-22)35-33(39)40-21-28-26-17-9-7-15-24(26)25-16-8-10-18-27(25)28/h1-18,28-30H,19-21H2,(H,34,36)(H,35,39)(H,37,38)/t29-,30-/m0/s1
InChI key:InChIKey=KZPTXQVSHOISSL-KYJUHHDHSA-N
SMILES:C(OC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4
Synonyms:
  • 2: PN: WO2023003984 SEQID: 2 claimed sequence
  • Fmoc-Phe-Phe-OH
  • L-Phenylalanine, N-[N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl]-
  • L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-L-phenylalanine
  • Fmoc-FF-OH
  • (2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoyl]amino]-3-phenylpropanoicacid
  • Fmoc-Phe-Phe
  • (S)-2-((S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-phenylpropanaMido)-3-phenylpropanoic acid
  • Fmoc-L-Phe-L-Phe-OH
  • See more synonyms
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