CAS: 850140-72-6 - Tovok,BIBW 2992

Formula: C₂₄H₂₅ClFN₅O₃

InChI: InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1

InChI key: InChIKey=ULXXDDBFHOBEHA-CWDCEQMOSA-N

SMILES: O=C(C=CCN(C)C)NC1=CC=2C(=NC=NC2NC3=CC=C(F)C(Cl)=C3)C=C1OC4COCC4

Synonyms:

• (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide
• (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl}-4-(dimethylamino)but-2-enamide
• (E)-N-(7-((S)-tetrahydrofuran-3-yloxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
• (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-dime
• 2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((3S)-tetrahydro-3-furanyl)oxy)-6-quinazolinyl)-4-(dimethylamino)-
• 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-
• Afatinib
• Bibw 2992
• Bibw2992
• Gilotrif
• Giotrif
• Tovok

Afatinib

CAS: 850140-72-6

• Formula: C₂₄H₂₅ClFN₅O₃
• Purity: >97.0%(HPLC)(N)
• Color and Shape: White to Orange to Green powder to crystal
• Molecular weight: 485.94

Afatinib (BIBW 2992)

CAS: 850140-72-6

• Formula: C₂₄H₂₅ClFN₅O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 485.95

Afatinib

CAS: 850140-72-6

• Formula: C₂₄H₂₅ClFN₅O₃
• Purity: By hplc: >99% (Typical Value in Batch COA)
• Color and Shape: white to off-white solid
• Molecular weight: 485.94g/mol

Afatinib

CAS: 850140-72-6

Afatinib (BIBW 2992) is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 …

• Formula: C₂₄H₂₅ClFN₅O₃
• Purity: 99.9%
• Color and Shape: Off-White Solid
• Molecular weight: 485.94

Afatinib-d4

CAS: 850140-72-6

• Formula: C₂₄H₂₁ClFN₅O₃D₄
• Molecular weight: 489.97

Afatinib, Free Base

CAS: 850140-72-6

• Purity: 99.0%
• Color and Shape: Solid
• Molecular weight: 485.94000244140625

Afatinib

CAS: 850140-72-6

Irreversible blocker of three members of the ErbB family (ErbB1, ErbB2/HER2, and ErbB4) with IC50 …

• Formula: C₂₄H₂₅ClFN₅O₃
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 485.94 g/mol

Afatinib - Bio-X ™

CAS: 850140-72-6

Afatinib is a small molecule that inhibits the activity of cellular kinases that are involved …

• Formula: C₂₄H₂₅ClFN₅O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 485.94 g/mol

Afatinib-d4

CAS: 850140-72-6

• Formula: C₂₄D₄H₂₁ClFN₅O₃
• Color and Shape: Neat
• Molecular weight: 489.963

Afatinib

CAS: 850140-72-6

Applications An aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, …

• Formula: C₂₄H₂₅ClFN₅O₃
• Color and Shape: White to Pale Yellow Solid
• Molecular weight: 485.94