CAS 850649-61-5

Alogliptin

Description:

Alogliptin is an oral antihyperglycemic agent belonging to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors, primarily used in the management of type 2 diabetes mellitus. Its mechanism of action involves the inhibition of the DPP-4 enzyme, which leads to increased levels of incretin hormones, thereby enhancing insulin secretion and reducing glucagon levels in a glucose-dependent manner. This helps to lower blood glucose levels. Alogliptin is characterized by its chemical formula, which includes elements such as carbon, hydrogen, nitrogen, and oxygen, contributing to its specific molecular structure. It is typically administered in tablet form and is often prescribed in combination with other antidiabetic medications to improve glycemic control. Alogliptin is generally well-tolerated, with a side effect profile that may include gastrointestinal disturbances and potential risk of pancreatitis. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and monitoring while using Alogliptin.

Formula: C₁₈H₂₁N₅O₂

InChI: InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1

InChI key: InChIKey=ZSBOMTDTBDDKMP-OAHLLOKOSA-N

SMILES: C(N1C(=CC(=O)N(C)C1=O)N2C[C@H](N)CCC2)C3=C(C#N)C=CC=C3

Synonyms:

• (R)-2-[6-[3-Aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-ylmethyl]benzonitrile
• 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile
• 2-[[6-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile
• Alogliptin(Alogliptine, Alogliptina)
• Benzonitrile, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-
• Vipidia
• Alogliptin

(R)​-​2-​[6-​[3-​Aminopiperidin-​1-​yl]​-​3-​methyl-​2,​4-​dioxo-​1,​2,​3,​4-​tetrahydropyrimidin-​1-​ylmethyl]​benzonitrile

CAS: 850649-61-5

Formula: C₁₈H₂₁N₅O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 339.3916

Ref: IN-DA00IDIW

Alogliptin

CAS: 850649-61-5

(R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile

Formula: C₁₈H₂₁N₅O₂

Purity: 98%

Molecular weight: 339.39

Ref: IN-DG113240

Alogliptin

CAS: 850649-61-5

Alogliptin

Formula: C₁₈H₂₁N₅O₂

Purity: 98%

Molecular weight: 339.397

Ref: 54-OR1027745

Alogliptin

CAS: 850649-61-5

Formula: C₁₈H₂₁N₅O₂

Molecular weight: 339.40

Ref: 4Z-A-4949

Alogliptin

CAS: 850649-61-5

Alogliptin

Formula: C₁₈H₂₁N₅O₂

Purity: ≥98%

Molecular weight: 339.39

Ref: 54-BUP08626

Alogliptin

CAS: 850649-61-5

Color and Shape: Neat

Ref: 86-MM3928.00

Alogliptin

CAS: 850649-61-5

Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9

Formula: C₁₈H₂₁N₅O₂

Purity: 99.63%

Color and Shape: Solid

Molecular weight: 339.39

Ref: TM-T6192

Alogliptin

CAS: 850649-61-5

Formula: C₁₈H₂₁N₅O₂

Molecular weight: 339.40

Ref: ST-EA-CP-A13000

Alogliptin

Controlled Product

CAS: 850649-61-5

Applications Alogliptin is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4).Antidiabetic agent.
References Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009);

Formula: C₁₈H₂₁N₅O₂

Color and Shape: Neat

Molecular weight: 339.39

Ref: TR-A575425

ALOGLIPTIN

CAS: 850649-61-5

Formula: C₁₈H₂₁N₅O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 339.399

Ref: 10-F468425

Alogliptin

CAS: 850649-61-5

Alogliptin is a drug that belongs to the class of glp-1 receptor agonists. It is used for the treatment of type 2 diabetes and can be prescribed alone or in combination with other drugs. Alogliptin has been shown to stimulate the production and release of peptide hormones, such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are important for the regulation of blood sugar levels. The drug also stimulates insulin release from pancreatic beta cells in response to blood sugar levels, which is necessary for maintaining normal blood sugar levels. Alogliptin has an effect on congestive heart failure by increasing cardiac output through improved contractility, as well as on gut motility through its activity on toll-like receptors.

Formula: C₁₈H₂₁N₅O₂

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 339.39 g/mol

Ref: 3D-FA17319