CAS 851881-59-9

(R)-ADX-47273

CAS: 851881-59-9

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).

Formula: C₂₀H₁₇F₂N₃O₂

Purity: 99.87%

Color and Shape: Solid

Molecular weight: 369.36

Ref: TM-T13441

(R)-ADX-47273

CAS: 851881-59-9

(R)-ADX-47273

Purity: ≥98%

Molecular weight: 369.36g/mol

Ref: 54-BUP09666

(R)-ADX 47273

CAS: 851881-59-9

Positive allosteric modulator of the metabotropic glutamate receptor mGluR5 with EC50 in submicromolar range. The compound is able to increase mGluR5 function in vitro and in vivo. A study showed that ADX-47273 enhanced fear extinction learning as well as improved reversal learning in experimental animals.

Formula: C₂₀H₁₇F₂N₃O₂

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 369.36 g/mol

Ref: 3D-BA166488