CAS 851881-59-9

Formula: C20H17F2N3O2

InChI: InChI=1S/C20H17F2N3O2/c21-16-7-3-13(4-8-16)18-23-19(27-24-18)15-2-1-11-25(12-15)20(26)14-5-9-17(22)10-6-14/h3-10,15H,1-2,11-12H2/t15-/m1/s1

InChI key: VXQCCZHCFBHTTD-OAHLLOKOSA-N

SMILES: C1C[C@H](CN(C1)C(=O)C2=CC=C(C=C2)F)C3=NC(=NO3)C4=CC=C(C=C4)F

(R)-ADX-47273

CAS: 851881-59-9

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).

Formula: C₂₀H₁₇F₂N₃O₂

Purity: 99.87%

Color and Shape: Solid

Molecular weight: 369.36

Ref: TM-T13441

(3R)-1-(4-fluorobenzoyl)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]piperidine

CAS: 851881-59-9

Ref: IN-DA01EOM6

(R)-ADX-47273

CAS: 851881-59-9

(R)-ADX-47273

Formula: C₂₀H₁₇F₂N₃O₂

Purity: ≥98%

Molecular weight: 369.36

Ref: 54-BUP09666

(R)-ADX 47273

CAS: 851881-59-9

Positive allosteric modulator of the metabotropic glutamate receptor mGluR5 with EC50 in submicromolar range. The compound is able to increase mGluR5 function in vitro and in vivo. A study showed that ADX-47273 enhanced fear extinction learning as well as improved reversal learning in experimental animals.

Formula: C₂₀H₁₇F₂N₃O₂

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 369.36 g/mol

Ref: 3D-BA166488