CAS 856867-55-5
:Tedizolid phosphate
Description:
Tedizolid phosphate is an oxazolidinone antibiotic that is primarily used for the treatment of acute bacterial skin and skin structure infections. It is a prodrug of tedizolid, which means it is converted into its active form in the body. The compound exhibits potent activity against a range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Tedizolid phosphate is characterized by its ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the formation of functional ribosomes. This mechanism of action makes it effective against resistant strains of bacteria. The substance is typically administered orally or intravenously and has a favorable pharmacokinetic profile, including a long half-life that allows for once-daily dosing. Additionally, tedizolid phosphate has been noted for its relatively low potential for drug-drug interactions and a favorable safety profile, making it a valuable option in the treatment of serious infections caused by resistant pathogens.
Formula:C17H18FN6O7P
InChI:InChI=1S/C17H16FN6O6P/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(30-17(24)25)9-29-31(26,27)28/h2-7,12H,8-9H2,1H3,(H2,26,27,28)/t12-/m1/s1
InChI key:InChIKey=QCGUSIANLFXSGE-GFCCVEGCSA-N
SMILES:O=C1N(C2=CC(F)=C(C=C2)C=3C=CC(=NC3)C=4N=NN(C)N4)C[C@H](COP(=O)(O)O)O1
Synonyms:- (5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-2-oxazolidinone
- (R)-(3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl dihydrogen phosphate
- 2-Oxazolidinone, 3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-, (5R)-
- Tedizolid hydrogen phosphate
- Tr 701Fa
- Tedizolid phosphate
- Torezolid phosphate
- (R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogenphosphate
- [(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
- Tedizolid Phosphate (TR-701)
- Tedizolid phosphate impurity A
- (R) -3- (4- (2- (2- methyl-tetrazol-5-yl) pyridin-5-yl) -3-fluorophenyl) -5-hydroxymethyl-oxazolidin-2-one phosphate
- Tedizolid phosphate (5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-2-oxazolidinone
- -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate
- (R)-(3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)met
- (R) -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate
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Found 10 products.
Tedizolid Phosphate
CAS:Controlled ProductFormula:C17H16FN6O6PColor and Shape:Off White SolidMolecular weight:450.32Tedizolid Phosphate
CAS:<p>Tedizolid Phosphate (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid.</p>Formula:C17H16FN6O6PPurity:97.96%Color and Shape:SolidMolecular weight:450.32Tedizolid phosphate
CAS:<p>Inhibitor of monoamine oxidase; anti-bacterial agent</p>Formula:C17H16FN6O6PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:450.32 g/molTedizolid Phosphate
CAS:Controlled Product<p>Applications Tedizolid, known as TR-700, is an oral and i.v administered intracellular antibacterial drug.<br>References Schaadt, R. et al.: Antimicrob. Agents Chemother., 53, 3236 (2009); Lemaire, S. et al.: J. Antimicrob. Chemother., 64, 1035 (2009)<br></p>Formula:C17H16FN6O6PColor and Shape:NeatMolecular weight:450.32
