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CAS 857478-30-9

:

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-isovaline

Description:
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-isovaline, commonly referred to as Fmoc-L-isovaline, is a derivative of the amino acid isovaline, modified with a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is characterized by its use in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective moiety for the amino group, allowing for selective coupling reactions. The Fmoc group is known for its stability under basic conditions and can be removed under mild acidic conditions, facilitating the sequential addition of amino acids in peptide chains. The presence of the isovaline side chain contributes to the compound's hydrophobic characteristics, influencing the overall properties of the peptides synthesized with it. Additionally, the fluorenyl group provides a chromophore that can be utilized in various analytical techniques, such as UV-Vis spectroscopy. Overall, Fmoc-L-isovaline is a valuable building block in the field of peptide chemistry, enabling the synthesis of diverse peptide sequences for research and therapeutic applications.
Formula:C20H21NO4
InChI:InChI=1/C20H21NO4/c1-3-20(2,18(22)23)21-19(24)25-12-17-15-10-6-4-8-13(15)14-9-5-7-11-16(14)17/h4-11,17H,3,12H2,1-2H3,(H,21,24)(H,22,23)/t20-/m0/s1
InChI key:DZSLHAJXIQCMLR-FQEVSTJZSA-N
SMILES:CC[C@@](C)(C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:
  • 857478-30-9
  • L-isovaline, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • N-FMoc--L-isovaline
  • Fmoc-IsoVal-OH
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl L-IsoValine
  • Fmoc-alpha-Et-D-Ala-OH
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanoic acid
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isovaline USP/EP/BP
  • Fmoc-L-isovaline |Fmoc-IsoVal-OH
  • Fmoc-L-isovaline, >97%
  • See more synonyms
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