CAS 86123-10-6
:Fmoc-D-Phenylalanine
Description:
Fmoc-D-Phenylalanine is a derivative of the amino acid phenylalanine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to its ability to protect the amino group of the amino acid while allowing for further reactions. Fmoc-D-Phenylalanine is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. The Fmoc group can be removed under basic conditions, facilitating the coupling of the protected amino acid to other amino acids in peptide chains. The D-configuration of phenylalanine in this compound indicates that it is the enantiomer that is not commonly found in natural proteins, making it useful for studying the effects of chirality in biological systems. Overall, Fmoc-D-Phenylalanine is a valuable reagent in the field of synthetic organic chemistry and biochemistry.
Formula:C24H20NO4
InChI:InChI=1/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)/p-1/t22-/m1/s1
SMILES:c1ccc(cc1)C[C@H](C(=O)[O-])N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:- FMOC-D-Phenylalanine-OH
- Fmoc-D-Phe-OH
- N-(9-Fluorenylmethoxycarbonyl)-D-phenylalanine
- Fmoc-D-Phc-OH
- NALPHA-9-Fluorenylmethoxycarbonyl-D-phenylalanine
- FmocAV21690
- N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine
- (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-phenylpropanoate
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Found 12 products.
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine
CAS:Formula:C24H21NO4Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:387.44Fmoc-D-Phe-OH
CAS:<p>Bachem ID: 4005952.</p>Formula:C24H21NO4Purity:99.9%Color and Shape:WhiteMolecular weight:387.44Fmoc-D-Phenylalanine
CAS:Fmoc-D-PhenylalanineFormula:C24H21NO4Purity:99%Color and Shape: off white solidMolecular weight:387.43g/molFmoc-D-Phe-OH
CAS:Formula:C24H21NO4Purity:≥ 98.0%Color and Shape:White to almost white powder or crystalsMolecular weight:387.44D-Phenyl-d5-alanine-2,3,3-d3-N-FMOC(Phenylalanine-l)
CAS:Formula:C6D5CD2CD(NFMOC)COOHPurity:98 atom % DMolecular weight:395.48Fmoc-D-Phe-OH
CAS:<p>M03371 - Fmoc-D-Phe-OH</p>Formula:C24H21NO4Purity:98%Color and Shape:Solid, Crystalline Powder or PowderMolecular weight:387.435FMOC-D-Phenylalanine extrapure, 99%
CAS:Formula:C24H21NO4Purity:min. 99%Color and Shape:White, Crystalline powderMolecular weight:387.40Fmoc-D-phenylalanine
CAS:<p>Fmoc-D-phenylalanine is a synthetic amino acid that is used as a substrate in solid-phase peptide synthesis. It binds to the enzyme D-phenylalanine racemase, which catalyzes the conversion of L-DOPA to dopamine, and also inhibits the enzyme D-amino acid oxidase, which converts L-DOPA to 3,4 dihydroxyphenylacetic acid. Fmoc-D-phenylalanine has been shown to inhibit tumor growth in mice by inhibiting integrin receptor binding and uptake of extracellular matrix proteins. This inhibition leads to decreased metastasis and tumor cell death. Fmoc-D-phenylalanine has also been shown to be an efficient method for synthesizing cyclic lipopeptides and cyclic peptides with antimicrobial activity.</p>Formula:C24H21NO4Purity:Min. 95%Color and Shape:PowderMolecular weight:387.43 g/mol
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