CAS 864445-54-5

Jwh 203

Description:

JWH-203 is a synthetic cannabinoid that belongs to a class of compounds known for their ability to bind to cannabinoid receptors in the brain, mimicking the effects of natural cannabinoids found in cannabis. It was developed by Dr. John W. Huffman and is part of a larger family of JWH compounds. JWH-203 is characterized by its high potency and selectivity for the CB1 receptor, which is primarily responsible for the psychoactive effects associated with cannabis use. The substance is typically encountered in research contexts and is not approved for medical use. Its chemical structure includes a naphthalene core, which contributes to its binding affinity. As with many synthetic cannabinoids, JWH-203 can exhibit unpredictable effects and poses potential health risks, including anxiety, paranoia, and other adverse reactions. Due to its synthetic nature and the potential for abuse, it is often subject to legal restrictions in various jurisdictions. Researchers continue to study its pharmacological properties to better understand its effects and potential implications for health and safety.

Formula: C₂₁H₂₂ClNO

InChI: InChI=1S/C21H22ClNO/c1-2-3-8-13-23-15-18(17-10-5-7-12-20(17)23)21(24)14-16-9-4-6-11-19(16)22/h4-7,9-12,15H,2-3,8,13-14H2,1H3

InChI key: InChIKey=YDINKDBAZJOSLV-UHFFFAOYSA-N

SMILES: C(CC1=C(Cl)C=CC=C1)(=O)C=2C=3C(N(CCCCC)C2)=CC=CC3

Synonyms:

• Ethanone, 2-(2-chlorophenyl)-1-(1-pentyl-1H-indol-3-yl)-
• 2-(2-chlorophenyl)-1-(1-pentyl-1H-indol-3-yl)ethanone
• JWH 203 (exempt preparation)
• JWH-203 (1.0 mg/mL in Methanol)
• 1-Pentyl-3-(2-chlorophenylacetyl)indole
• 2-(2-Chlorophenyl)-1-(1-pentylindol-3-yl)ethanone

JWH-203

Controlled Product

CAS: 864445-54-5

Applications A cannabimimetic indole derivative that acts as both a cannabinoid receptor CB1 and CB2 agonist. Synthetic Cannabinoids
References Huffman J.W. et al.: Bioorg. Med. Chem. Lett., 15, 4110 (2005); De Freitas, G.B.L. et al.: Eur. J. Med. Chem., 44, 2482 (2009); Tuccinardi, T. et al.: J. Med. Chem., 49, 984 (2006);

Formula: C₂₁H₂₂ClNO

Color and Shape: Off White Solid

Molecular weight: 339.86

Ref: TR-J211450

JWH-203 (1 mg/mL in Methanol)

Controlled Product

CAS: 864445-54-5

Formula: C₂₁H₂₂ClNO

Color and Shape: Single Solution

Molecular weight: 339.86

Ref: TR-KIT8485

JWH 203

Controlled Product

CAS: 864445-54-5

JWH 203 is a synthetic cannabinoid, which is used as an analytical reference standard for the detection of other synthetic cannabinoids. It is a designer drug, which has been shown to have similar effects on locomotor activity and cb2 receptor binding as the natural cannabinoid anandamide. JWH 203 can be detected in urine samples by LC-MS/MS and LC-HRMS methods. The chemical structure of JWH 203 includes a hydroxyl group and an alkyl chain with two methyl groups at the terminal end. This compound is not active in humans, but has been shown to function as an antagonist of the CB1 receptor (Rimonabant).

Formula: C₂₁H₂₂ClNO

Purity: Min. 95%

Molecular weight: 339.86 g/mol

Ref: 3D-FJ24750

JWH-203 (2-(2-Chlorophenyl)-1-(1-pentylindol-3-yl)ethanone) 0.1 mg/ml in Acetonitrile

Controlled Product

CAS: 864445-54-5

Color and Shape: Single Solution

Ref: 61-AMP1275.70-12

JWH-203 (2-(2-Chlorophenyl)-1-(1-pentylindol-3-yl)ethanone)

Controlled Product

CAS: 864445-54-5

Color and Shape: Neat

Ref: 61-FOR1275.70