
CAS 865362-74-9
:FR180204
Description:
FR180204, with the CAS number 865362-74-9, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is characterized as a selective inhibitor of certain protein kinases, which play crucial roles in various cellular processes, including cell growth, differentiation, and metabolism. The compound exhibits a specific binding affinity to its target, making it a valuable tool in research aimed at understanding kinase-related pathways and their implications in diseases such as cancer. In terms of its physical properties, FR180204 is typically described as a solid at room temperature, with solubility in organic solvents. Its molecular structure includes functional groups that contribute to its biological activity and selectivity. As with many experimental compounds, further studies are necessary to fully elucidate its pharmacokinetics, toxicity, and potential therapeutic efficacy in clinical settings. Overall, FR180204 represents a promising candidate for further investigation in drug development.
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 8 products.
ERK Inhibitor II, FR180204
CAS:Formula:C18H13N7Purity:98%Color and Shape:SolidMolecular weight:327.3427FR 180204
CAS:Formula:C18H13N7Purity:>98.0%(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:327.35FR 180204 [Optimized for Cell Culture]
CAS:Formula:C18H13N7Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:327.35FR 180204
CAS:<p>FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.</p>Formula:C18H13N7Purity:98% - 99.74%Color and Shape:SolidMolecular weight:327.34ERK Inhibitor II, FR180204
CAS:<p>ERK inhibitor II (FR180204) is a type of protein kinase inhibitor that has been shown to inhibit the activity of ERK1/2, which are mitogen-activated protein kinases. The biological properties of this compound have been studied in vitro and in a model system using hl-60 cells. The compound has been shown to inhibit angiogenic processes, such as epithelial mesenchymal transition and the cytosolic calcium ion levels. It also inhibits brain functions and growth factor-β1 synthesis, leading to apoptosis in pluripotent cells. This drug is being developed for the treatment of cancer, among other diseases. <br>ERK inhibitor II also inhibits pro-apoptotic proteins and signal pathways such as NFκB, PI3K/Akt, p38 MAPKs, JNKs, ERKs, and p53 activation.</p>Formula:C18H13N7Purity:Min. 95%Molecular weight:327.34 g/mol





