CAS 865479-71-6

Rivaroxaban R-enantiomer ((R)-5-Chloro-N-({2-oxo-3-[4-(3-oxomorpholino)phenyl]oxazolidin-5-yl}methyl)thiophene-2-carboxamide)

CAS: 865479-71-6

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₉H₁₈ClN₃O₅S

Color and Shape: Yellow White Solid

Molecular weight: 435.06557

Ref: 45-1604541

5-R-Rivaroxaban

CAS: 865479-71-6

5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.

Formula: C₁₉H₁₈ClN₃O₅S

Purity: 99.75%

Color and Shape: Solid

Molecular weight: 435.88

Ref: TM-T10174

5-R-Rivaroxaban

CAS: 865479-71-6

Formula: C₁₉H₁₈ClN₃O₅S

Purity: 99%

Color and Shape: Solid

Molecular weight: 435.8813

Ref: IN-DA00GU05

Rivaroxaban EP Impurity A

CAS: 865479-71-6

Formula: C₁₉H₁₈ClN₃O₅S

Color and Shape: White To Off-White Solid

Molecular weight: 435.88

Ref: 4Z-R-296

5-R-Rivaroxaban

CAS: 865479-71-6

5-R-Rivaroxaban

Purity: ≥98%

Molecular weight: 435.88g/mol

Ref: 54-BUP11186

(R)-Rivaroxaban (5-Chloro-N-[[(5R)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-

Controlled Product

CAS: 865479-71-6

Formula: C₁₉H₁₈ClN₃O₅S

Color and Shape: Neat

Molecular weight: 435.88

Ref: 86-MM3629.01

ent-Rivaroxaban

CAS: 865479-71-6

Applications ent-Rivaroxaban is the R-isomer of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.
References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),

Formula: C₁₉H₁₈ClN₃O₅S

Color and Shape: White To Off-White

Molecular weight: 435.88

Ref: TR-R538005

Rivaroxaban EP Impurity A

CAS: 865479-71-6

Formula: C₁₉H₁₈CIN₃O₅S

Molecular weight: 435.88

Ref: ST-EA-CP-R17001

5-R-Rivaroxaban

CAS: 865479-71-6

Color and Shape: Solid

Molecular weight: 435.88

Ref: 10-F987646

5-Chloro-N-[[(5R)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide

CAS: 865479-71-6

5-chloro-N-[[(5R)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide (CTP) is a potent inhibitor of the cytochrome P450 enzyme CYP3A4. CTP has been shown to inhibit the metabolism of midazolam, an important drug for general anesthesia and sedation, in a study investigating the interaction between CYP3A4 inhibitors and midazolam. Ketoconazole, another inhibitor of CYP3A4, inhibited the metabolism of midazolam in vitro as well. In addition, CTP was shown to be a substrate for CYP2D6 and CYP1A2 in vitro.

Formula: C₁₉H₁₈ClN₃O₅S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 435.88 g/mol

Ref: 3D-IC71688

ent-Rivaroxaban-d4

Controlled Product

CAS: 865479-71-6

Formula: C₁₉D₄H₁₄ClN₃O₅S

Color and Shape: Neat

Molecular weight: 439.906

Ref: TR-R538007