CAS 865479-71-6
:Formula:C19H18ClN3O5S
InChI:InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m1/s1
InChI key:KGFYHTZWPPHNLQ-CQSZACIVSA-N
SMILES:C1COCC(=O)N1C2=CC=C(C=C2)N3C[C@H](OC3=O)CNC(=O)C4=CC=C(S4)Cl
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Rivaroxaban R-enantiomer
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C19H18ClN3O5SColor and Shape:Yellow White SolidMolecular weight:435.065575-R-Rivaroxaban
CAS:5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.Formula:C19H18ClN3O5SPurity:99.75%Color and Shape:White SolidMolecular weight:435.881Rivaroxaban EP Impurity A
CAS:Formula:C19H18ClN3O5SColor and Shape:White To Off-White SolidMolecular weight:435.88(R)-Rivaroxaban (5-Chloro-N-[[(5R)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide)
CAS:Controlled ProductFormula:C19H18ClN3O5SColor and Shape:NeatMolecular weight:435.885-Chloro-N-[[(5R)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
CAS:Formula:C19H18ClN3O5SPurity:99%Color and Shape:SolidMolecular weight:435.8813ent-Rivaroxaban
CAS:Applications ent-Rivaroxaban is the R-isomer of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.
References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),Formula:C19H18ClN3O5SColor and Shape:NeatMolecular weight:435.885-R-Rivaroxaban
CAS:(R)-5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamideFormula:C19H18ClN3O5SPurity:99%Molecular weight:435.885-Chloro-N-[[(5R)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
CAS:5-chloro-N-[[(5R)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide (CTP) is a potent inhibitor of the cytochrome P450 enzyme CYP3A4. CTP has been shown to inhibit the metabolism of midazolam, an important drug for general anesthesia and sedation, in a study investigating the interaction between CYP3A4 inhibitors and midazolam. Ketoconazole, another inhibitor of CYP3A4, inhibited the metabolism of midazolam in vitro as well. In addition, CTP was shown to be a substrate for CYP2D6 and CYP1A2 in vitro.Formula:C19H18ClN3O5SPurity:Min. 95%Color and Shape:White PowderMolecular weight:435.88 g/molent-Rivaroxaban-d4
CAS:Controlled ProductFormula:C19D4H14ClN3O5SColor and Shape:NeatMolecular weight:439.906
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