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CAS 866460-33-5

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Setipiprant

Description:
Setipiprant is a chemical compound primarily known for its role as a selective antagonist of the prostaglandin D2 receptor 2 (DP2), which is implicated in various allergic and inflammatory conditions. It is classified as a small molecule and has been investigated for its potential therapeutic applications in treating conditions such as asthma and allergic rhinitis. The molecular structure of Setipiprant includes a core that allows for specific binding to the DP2 receptor, thereby inhibiting its activity. This action can lead to a reduction in inflammation and other symptoms associated with allergic responses. Setipiprant is typically administered in oral form and has undergone various clinical trials to assess its efficacy and safety profile. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are important for understanding its therapeutic potential and dosing regimens. Overall, Setipiprant represents a promising avenue in the development of targeted therapies for allergic diseases.
Formula:C24H19FN2O3
InChI:InChI=1S/C24H19FN2O3/c25-16-8-9-21-19(12-16)20-13-26(11-10-22(20)27(21)14-23(28)29)24(30)18-7-3-5-15-4-1-2-6-17(15)18/h1-9,12H,10-11,13-14H2,(H,28,29)
InChI key:InChIKey=IHAXLPDVOWLUOS-UHFFFAOYSA-N
SMILES:C(C(O)=O)N1C2=C(C=3C1=CC=C(F)C3)CN(C(=O)C=4C5=C(C=CC4)C=CC=C5)CC2
Synonyms:
  • ACT 129968
  • 2-(2-(1-Naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid
  • Setipiprant
  • 8-Fluoro-1,2,3,4-tetrahydro-2-(1-naphthalenylcarbonyl)-5H-pyrido[4,3-b]indole-5-acetic acid
  • 5H-Pyrido[4,3-b]indole-5-acetic acid, 8-fluoro-1,2,3,4-tetrahydro-2-(1-naphthalenylcarbonyl)-
  • setipplant
  • 2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid(Setipiprant,ACT129968)
  • Setipiprant(ACT-129968, KYTH-105)
  • 2-(2-(1-phthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid
  • ACT129968;ACT-129968;ACT 129968
  • See more synonyms
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