CAS 867-44-7

S-Methylisothiourea hemisulfate

Description:

S-Methylisothiourea hemisulfate is a chemical compound characterized by its role as a potent inhibitor of nitric oxide synthase and its application in various biochemical research contexts. It is a derivative of isothiourea, featuring a methyl group attached to the sulfur atom, which enhances its biological activity. The compound is typically encountered as a white to off-white crystalline solid, soluble in water and other polar solvents, making it suitable for laboratory use. Its molecular structure includes a thiourea moiety, which is known for its ability to form hydrogen bonds and participate in various chemical reactions. S-Methylisothiourea hemisulfate is often utilized in studies related to nitric oxide signaling pathways, as well as in the investigation of neuroprotective mechanisms. Safety precautions should be observed when handling this compound, as it may pose health risks if ingested or inhaled. Proper storage conditions, such as keeping it in a cool, dry place away from light, are recommended to maintain its stability and efficacy.

Formula: C₂H₆N₂SH₂O₄S

InChI: InChI=1S/C2H6N2S.H2O4S/c1-5-2(3)4;1-5(2,3)4/h1H3,(H3,3,4);(H2,1,2,3,4)

InChI key: InChIKey=NNBBQNFHCVVQHZ-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)O.C(SC)(=N)N

Synonyms:

• 2-Methyl-2-thiopseudourea sulfate (2:1)
• Bis(2-methylisothiouronium) sulphate
• Bis(S-methylisothiouronium) sulfate
• Carbamimidothioic acid, methyl-, sulfate (2:1)
• Methylcarbamimidothioate sulfate (2:1)
• Methylisothiourea sulfate (2:1)
• Methylthioformamidine sulfate (2:1)
• Pseudourea, 2-methyl-2-thio-, sulfate (2:1)
• S-Methyl-iso-thiourea sulfate
• S-Methylisothioura hemisulfate
• S-Methylisothiourea Sulphate
• S-Methylisothiourea hemisulfate
• S-Methylisothiourea hemisulfuric acid salt
• S-Methylisothiourea semisulfate
• S-Methylisothiourea sulfate
• S-Methylisothiourea sulfate (2:1)
• S-Methylisothiouronium hemisulfate
• S-Methylthiopseudourea sulfate
• S-Methylthiouronium sulfate (2:1)

S-Methylisothiourea Sulfate

CAS: 867-44-7

Formula: C₄H₁₂N₄S₂·H₂SO₄

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 278.36

Ref: 3B-M0442

S-Methylisothiouronium sulfate, 98+%

CAS: 867-44-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₁₄N₄O₄S₃

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder or fused solid, White

Molecular weight: 278.36

Ref: 02-A11044

2-Methyl-2-Thiopseudourea Sulfate

CAS: 867-44-7

Formula: C₄H₁₄N₄O₄S₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 278.3734

Ref: IN-DA0033DZ

S-Methylisothiourea sulfate

CAS: 867-44-7

S-Methylisothiourea sulfate

Formula: C₂H₆N₂SH₂O₄S

Purity: ≥98%

Molecular weight: 139.18

Ref: 54-BUP16046

S-Methylisothiourea hemisulfate salt

CAS: 867-44-7

Formula: C₄H₁₂N₄S₂H₂SO₄

Purity: ≥ 99.0%

Color and Shape: White to off white crystalline powder

Molecular weight: 278.38

Ref: 7W-GL0540

S-Methylisothiourea sulfate

CAS: 867-44-7

S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic

Formula: C₂H₆N₂SH₂O₄S

Purity: 99.58%

Color and Shape: White Solid

Molecular weight: 139.18

Ref: TM-T22419

S-Methylisothiouronium sulfate

CAS: 867-44-7

S-Methylisothiouronium sulfate (SMTS) is a drug that is used as an antidiabetic agent. It has been shown to increase insulin sensitivity and lower plasma glucose levels, which may be due to its ability to inhibit the activity of creatine kinase. In addition, SMTS increases cytosolic calcium levels and has been shown to be effective in the treatment of obesity and type 2 diabetes. This drug binds selectively to guanidinoacetate receptors, which are involved in the regulation of blood sugar levels. SMTS inhibits the activity of other enzymes, such as amines and chloride, leading to increased insulin sensitivity.

Formula: C₄H₁₂N₄S₂·H₂SO₄

Color and Shape: White Off-White Powder

Molecular weight: 278.38 g/mol

Ref: 3D-FM11158

S-Methylisothiourea (sulfate)

CAS: 867-44-7

Purity: 98%

Molecular weight: 186.2

Ref: 10-F986701

S-Methyl-isothiouronium Hemisulfate

Controlled Product

CAS: 867-44-7

Applications Intermediate of 4-Hydroxydebrisoquine. S-Methyl-isothiouronium Hemisulfate is also a reagent used in the synthesis of strobilurin-pyrimidine derivatives for their anti-proliferative activity.
References Young, R.C., et al.: J. Med. Chem., 31, 670 (1988); Chai, B. et al.: Bioorg. Med. Chem. Lett., 23, 3505 (2013);

Formula: C₂H₆N₂SH₂SO₄

Color and Shape: Neat

Molecular weight: 139.14

Ref: TR-M314960

S-Methylisothiourea sulfate

CAS: 867-44-7

2-Methyl-2-thiopseudourea hemisulfate

Formula: C₄H₁₄N₄O₄S₃

Purity: 97%

Molecular weight: 278.37

Ref: IN-DG22908

2-Methyl-2-thiopseudourea hemisulfate

CAS: 867-44-7

Formula: C₄H₁₄N₄O₄S₃

Purity: 97%

Color and Shape: Solid, White - Almost white powder

Molecular weight: 278.36

Ref: 10-F221462