CAS 87-33-2: Isosorbide dinitrate

Description:Isosorbide dinitrate (ISDN) is an organic nitrate compound primarily used as a vasodilator in the treatment of angina pectoris and heart failure. It is a colorless to pale yellow crystalline solid that is soluble in water and organic solvents. The chemical formula for isosorbide dinitrate is C7H10N2O5, and it features two nitrate groups esterified to the isosorbide backbone. ISDN acts by releasing nitric oxide, which relaxes vascular smooth muscle, leading to the dilation of blood vessels and improved blood flow. The compound is typically administered in oral or sublingual forms, and its pharmacokinetics include a rapid onset of action with a relatively short half-life. Common side effects may include headaches, dizziness, and hypotension. Due to its potential for tolerance development, dosing regimens often involve intermittent use. Isosorbide dinitrate is also utilized in research settings to study vascular function and nitric oxide signaling pathways. Safety precautions are necessary when handling this compound, as it can be sensitive to heat and shock.

Formula:C₆H₈N₂O₈

InChI:InChI=1S/C6H8N2O8/c9-7(10)15-3-1-13-6-4(16-8(11)12)2-14-5(3)6/h3-6H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key:InChIKey=MOYKHGMNXAOIAT-JGWLITMVSA-N

SMILES:O=N(=O)OC1COC2C(ON(=O)=O)COC12

Synonyms:
1,4,3,6-Sorbido-2,5-dinitric acid ester
1,4:3,6-Dianhydro-D-glucitol 2,5-dinitrate
1,4:3,6-Dianhydro-D-sorbitol 2,5-dinitrate
1,4:3,6-Dianhydro-D-glucitol 2,5-dinitrate
1,4:3,6-Dianhydro-D-sorbitol 2,5-dinitrate
1,4:3,6-Dianhydrosorbitol 2,5-dinitrate
D-Glucitol, 1,4:3,6-dianhydro-, 2,5-dinitrate
D-Glucitol, 1,4:3,6-dianhydro-, dinitrate
D-Isosorbide dinitrate
Astridine
See more synonyms
Cardiket
Cardio 10
Cardis
Carvanil
Carvasin
Cedocard
Claodical
Corosorbide
Corovliss
D-Glucitol, 1,4:3,6-dianhydro-, 2,5-dinitrate
D-Isosorbide dinitrate
Dignionitrat
Dilatrate
Dilatrate SR
Diniket
Dinitrate d'isosorbide
Dinitrato De Isosorbida
Dinitroisosorbide
Dinitrosorbide
Disorlon
Duranitrat
EureCor
Ev 151
Flindix
Frandol
Furo[3,2-b]furan, D-glucitol deriv.
Glentonin
Glucitol, 1,4:3,6-dianhydro-, dinitrate
Glucitol, 1,4:3,6-dianhydro-, dinitrate, D-
Glucitol, 1,4:3,6-dianhydro-, dinitrate, D-
Harrical
IBD
Imtack
Isdin
Isdn
Iso-Bid
Iso-Mack
Iso-Puren
Isocard
Isocore
Isodinit
Isoket
Isoket retard 40
Isonate?
Isorbid
Isordil
Isordil Tembids
Isosorbiddinitrat
Isosorbide 2,5-dinitrate
Isosorbide Dinitrate
Isosorbide dinitrate mixture
Isosorbide nitrate
Isostenase
Isotrate
Korodil
Langoran
Laserdil
Maycor
Mixture, Isosorbide Dinitrate
Myorexon
Nitorol
Nitrofix
Nitrol
Nitrosorbid
Nitrosorbide
Nitrosorbonl Nosim
Nsc 80038
Resoidan
Rifloc Retard
Rigedal
Risordan
Sdm 25
Sdm 40
Soni-Slo
Sorbangil
Sorbichew
Sorbid SA
Sorbide dinitrate
Sorbide nitrate
Sorbidilat
Sorbidnitrate
Sorbitol, 1,4:3,6-dianhydro-, dinitrate
Sorbitrate
Sorbonit
Sorbopercuten
Sorquad
Tyb 3215
Vascardin
Vasorbate
Vasotrate
1,4:3,6-dianhydro-2,5-di-O-nitrohexitol
D-Glucitol, 1,4:3,6-dianhydro-, dinitrate
1,4:3,6-dianhydro-2,5-di-O-nitro-D-glucitol
Isosobide dinitrate

Found 8 products.

Product data	Purity	Price range	Estimated delivery
Isosorbide dinitrate CRS REF: 41-I0775000CAS: 87-33-2	- - -	115.00 €	Tue 29 Apr 25
Diluted Isosorbide Dinitrate REF: 45-1353000CAS: 87-33-2	- - -	532.00 €	Wed 30 Apr 25
Isosorbide Dinitrate REF: IN-DA003R5MCAS: 87-33-2	95%	29.00 €~502.00 €	Fri 02 May 25
Isosorbide dinitrate REF: TM-T1479CAS: 87-33-2	99.72%	35.00 €~487.00 €	Fri 02 May 25
Isosorbide dinitrate REF: 7W-GC6329CAS: 87-33-2	- - -	To inquire	Fri 02 May 25
Isosorbide Dinitrate REF: 4Z-I-194CAS: 87-33-2	- - -	To inquire	Thu 08 May 25
Isosorbide dinitrate - 60% lactose and 40% Isosorbide dinitrate REF: 3D-MI09907CAS: 87-33-2	Min. 95%	143.00 €~1,627.00 €	Mon 12 May 25
Isosorbide dinitrate REF: 47-206CAS: 87-33-2	- - -	- - -	Discontinued product