CAS 871224-64-5: Almorexant

Description: Almorexant is a chemical compound classified as a dual orexin receptor antagonist, primarily investigated for its potential use in treating insomnia and other sleep disorders. It functions by selectively blocking the action of orexin neuropeptides, which play a crucial role in regulating arousal, wakefulness, and appetite. The molecular structure of Almorexant features a complex arrangement that contributes to its pharmacological activity, although specific details about its physical properties, such as solubility and stability, are typically found in specialized databases or scientific literature. Almorexant has undergone various clinical trials to assess its efficacy and safety profile, demonstrating promise in promoting sleep without the adverse effects commonly associated with traditional sedatives. As with many investigational drugs, its development status may vary, and ongoing research continues to explore its full therapeutic potential and mechanism of action.

Formula: C₂₉H₃₁F₃N₂O₃

InChI: InChI=1S/C29H31F3N2O3/c1-33-28(35)27(20-7-5-4-6-8-20)34-16-15-21-17-25(36-2)26(37-3)18-23(21)24(34)14-11-19-9-12-22(13-10-19)29(30,31)32/h4-10,12-13,17-18,24,27H,11,14-16H2,1-3H3,(H,33,35)/t24-,27+/m0/s1

InChI key: InChIKey=DKMACHNQISHMDN-RPLLCQBOSA-N

SMILES: O=C(NC)C(C=1C=CC=CC1)N2CCC3=CC(OC)=C(OC)C=C3C2CCC4=CC=C(C=C4)C(F)(F)F

Synonyms:

• (R)-2-((R)-6,7-Dimethoxy-1-(4-(Trifluoromethyl)Phenethyl)-3,4-Dihydroisoquinolin-2(1H)-Yl)-N-Methyl-2-Phenylacetamide
• (αR,1S)-3,4-Dihydro-6,7-dimethoxy-N-methyl-α-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-2(1H)-isoquinolineacetamide
• 2(1H)-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-N-methyl-α-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-, (αR,1S)-
• Act-078573
• Act-078573(R)-2-((R)-6,7-dimethoxy-1-(4-(trifluoromethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide
• Almorexant
• AlMorexant (hydrochloride)

Almorexant

CAS: 871224-64-5

• Purity: ≥98%
• Molecular weight: 512.56g/mol

Almorexant-13C-d3

CAS: 871224-64-5

• Formula: C₂₈₁₃CH₂₈D₃F₃N₂O₃
• Color and Shape: Pale Yellow Solid
• Molecular weight: 516.58

Almorexant

CAS: 871224-64-5

• Formula: C₂₉H₃₁F₃N₂O₃
• Color and Shape: Pale Yellow Solid
• Molecular weight: 512.58

Almorexant

CAS: 871224-64-5

Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for …

• Formula: C₂₉H₃₁F₃N₂O₃
• Purity: 97.75% - 98.02%
• Color and Shape: Solid
• Molecular weight: 512.56

Almorexant

CAS: 871224-64-5

Please enquire for more information about Almorexant including the price, delivery time and more detailed …

• Formula: C₂₉H₃₁F₃N₂O₃
• Purity: Min. 95%
• Molecular weight: 512.56 g/mol