CAS: 871700-17-3 - N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide

Formula: C₂₆H₂₃FIN₅O₄

InChI: InChI=1S/C26H23FIN5O4/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34)

InChI key: InChIKey=LIRYPHYGHXZJBZ-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=CC(=C1)N2C(=O)N(C(=O)C3=C(NC4=CC=C(I)C=C4F)N(C(=O)C(=C32)C)C)C5CC5)C

Synonyms:

• Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-
• G 02442104
• Gsk 212
• Gsk-1120212
• Jtp 74057
• Mekinist
• N-[3-[3-Cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
• Trametinib

Trametinib-d4

CAS: 871700-17-3

• Formula: C₂₆H₁₉D₄FIN₅O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 619.43

Trametinib

CAS: 871700-17-3

• Formula: C₂₆H₂₃FIN₅O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 615.40

Trametinib-13C-d3

CAS: 871700-17-3

• Formula: C₂₅₁₃CH₂₀D₃FIN₅O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 619.41

Trametinib-d6

CAS: 871700-17-3

• Formula: C₂₆H₁₇FIN₅O₄D₆
• Color and Shape: Off-White Solid
• Molecular weight: 621.44

Trametinib

CAS: 871700-17-3

Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP …

• Formula: C₂₆H₂₃FIN₅O₄
• Purity: 99.88%
• Color and Shape: Solid
• Molecular weight: 615.39

GSK1120212

CAS: 871700-17-3

Trametinib-13C6

CAS: 871700-17-3

Applications Trametinib-13C6 is the labelled compound form of Trametinib (C988930), which is used in the …

• Formula: C₂₀C₆H₂₃FIN₅O₄
• Color and Shape: White to Off-White Solid
• Molecular weight: 621.351

Trametinib

CAS: 871700-17-3

Applications Used in the systematic treatment of advanced cutaneous melanoma. An EGFR kinase inhibitor and …

• Formula: C₂₆H₂₃FIN₅O₄
• Color and Shape: Off-White
• Molecular weight: 615.39

Trametinib-d4

CAS: 871700-17-3

• Formula: C₂₆D₄H₁₉FIN₅O₄
• Molecular weight: 619.419

Trametinib

CAS: 871700-17-3

Inhibitor of MEK kinase; anti-neoplastic

• Formula: C₂₆H₂₃O₄N₅FI
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 615.39 g/mol