CAS 87233-62-3

Emedastine difumarate

Description:

Emedastine difumarate is an antihistamine compound primarily used in the treatment of allergic conjunctivitis. It functions as a selective H1 receptor antagonist, effectively alleviating symptoms such as itching, redness, and swelling associated with allergic reactions in the eyes. The substance is characterized by its ability to penetrate ocular tissues, providing localized relief with minimal systemic absorption. Emedastine difumarate is typically formulated as an eye drop solution, ensuring direct application to the affected area. Its chemical structure includes a difumarate salt form, which enhances its solubility and stability in aqueous solutions. The compound is generally well-tolerated, with a low incidence of side effects, making it a preferred choice in ophthalmic formulations. Additionally, it is important to store this substance in a cool, dry place, away from light, to maintain its efficacy. Overall, emedastine difumarate represents a valuable therapeutic option for managing allergic eye conditions.

Formula: C₁₇H₂₆N₄O·2C₄H₄O₄

InChI: InChI=1S/C17H26N4O.C4H4O4/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20;5-3(6)1-2-4(7)8/h4-5,7-8H,3,6,9-14H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key: InChIKey=FGFODSDYSQTNOS-WLHGVMLRSA-N

SMILES: C(COCC)N1C(=NC=2C1=CC=CC2)N3CCCN(C)CC3.C(=C/C(O)=O)\C(O)=O

Synonyms:

• 1-(2-Ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate
• 1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepin-1-yl)benzimidazole fumarate (1:2)
• 1-(2-Ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole fumarate (1:2)
• 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole di[(2E)-but-2-enedioate]
• 1H-1,4-Diazepine, 1H-benzimidazole deriv.
• 1H-Benzimidazole, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-, (2E)-2-butenedioate (1:2)
• 1H-Benzimidazole, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-, (E)-2-butenedioate (1:2)
• Al 3432A
• Benzimidazole, 1-(2-ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepin-1-yl)-, fumarate (1:2)
• Emadine
• Emedastine
• Kb-2413
• Kg-2413
• Ly 188695
• Rapimine
• Unii-42Mb94Qosm

EMEDASTINE DIFUMARATE CRS

CAS: 87233-62-3

EMEDASTINE DIFUMARATE CRS

Formula: C₂₅H₃₄N₄O₉

Color and Shape: Added

Molecular weight: 534.5589

Ref: 41-Y0000537

Emedastine Difumarate

CAS: 87233-62-3

Antihistamines

Formula: C₁₇H₂₆N₄O·2C₄H₄O₄

Color and Shape: White Yellow Powder

Molecular weight: 302.21066

Ref: 45-1234806

Emedastine fumarate

CAS: 87233-62-3

Formula: C₂₅H₃₄N₄O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 534.5589

Ref: IN-DA00GXW3

Emedastine Difumarate

CAS: 87233-62-3

Formula: C₁₇H₂₆N₄O·2C₄H₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 302.42 2*116.07

Ref: 4Z-E-341

Emedastine Difumarate

CAS: 87233-62-3

Emedastine Difumarate

Purity: 98%

Molecular weight: 534.57g/mol

Ref: 54-OR1025686

Emedastine Difumarate

CAS: 87233-62-3

Emedastine Difumarate, an H1 receptor blocker for allergic conjunctivitis, reduces histamine-induced eye inflammation.

Formula: C₂₅H₃₄N₄O₉

Color and Shape: Solid

Molecular weight: 534.56

Ref: TM-T21388

Emedastine Difumerate

Controlled Product

CAS: 87233-62-3

Applications Emedastine Difumerate acts as a leukotriene receptor antagonist and antihistamine in the treatment of asthma patients.
References Nishimura, M. et al.: Kur. Med. J., 58, 9 (2011); Sanchis-Merino, M. et al.: Exp. Eye Res., 86, 791 (2008);

Formula: C₁₇H₂₆N₄O·2C₄H₄O₄

Color and Shape: Neat

Molecular weight: 534.56

Ref: TR-E521520

Emedastine Difumarate

CAS: 87233-62-3

Color and Shape: Neat

Ref: 61-FOR1277.00