CAS 87233-62-3
:Emedastine difumarate
Description:
Emedastine difumarate is an antihistamine compound primarily used in the treatment of allergic conjunctivitis. It functions as a selective H1 receptor antagonist, effectively alleviating symptoms such as itching, redness, and swelling associated with allergic reactions in the eyes. The substance is characterized by its ability to penetrate ocular tissues, providing localized relief with minimal systemic absorption. Emedastine difumarate is typically formulated as an eye drop solution, ensuring direct application to the affected area. Its chemical structure includes a difumarate salt form, which enhances its solubility and stability in aqueous solutions. The compound is generally well-tolerated, with a low incidence of side effects, making it a preferred choice in ophthalmic formulations. Additionally, it is important to store this substance in a cool, dry place, away from light, to maintain its efficacy. Overall, emedastine difumarate represents a valuable therapeutic option for managing allergic eye conditions.
Formula:C17H26N4O·2C4H4O4
InChI:InChI=1S/C17H26N4O.C4H4O4/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20;5-3(6)1-2-4(7)8/h4-5,7-8H,3,6,9-14H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
InChI key:InChIKey=FGFODSDYSQTNOS-WLHGVMLRSA-N
SMILES:C(COCC)N1C(=NC=2C1=CC=CC2)N3CCCN(C)CC3.C(=C/C(O)=O)\C(O)=O
Synonyms:- 1-(2-Ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate
- 1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepin-1-yl)benzimidazole fumarate (1:2)
- 1-(2-Ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole fumarate (1:2)
- 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole di[(2E)-but-2-enedioate]
- 1H-1,4-Diazepine, 1H-benzimidazole deriv.
- 1H-Benzimidazole, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-, (2E)-2-butenedioate (1:2)
- 1H-Benzimidazole, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-, (E)-2-butenedioate (1:2)
- Al 3432A
- Benzimidazole, 1-(2-ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepin-1-yl)-, fumarate (1:2)
- Emadine
- Emedastine
- Kb-2413
- Kg-2413
- Ly 188695
- Rapimine
- Unii-42Mb94Qosm
- See more synonyms
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EMEDASTINE DIFUMARATE CRS
CAS:EMEDASTINE DIFUMARATE CRSFormula:C25H34N4O9Color and Shape:AddedMolecular weight:534.5589Emedastine Difumarate
CAS:AntihistaminesFormula:C17H26N4O·2C4H4O4Color and Shape:White Yellow PowderMolecular weight:302.21066Emedastine Difumarate
CAS:Formula:C17H26N4O·2C4H4O4Color and Shape:White To Off-White SolidMolecular weight:302.42 2*116.07Emedastine Difumarate
CAS:Emedastine Difumarate, an H1 receptor blocker for allergic conjunctivitis, reduces histamine-induced eye inflammation.Formula:C25H34N4O9Color and Shape:SolidMolecular weight:534.56Emedastine Difumerate
CAS:Controlled ProductApplications Emedastine Difumerate acts as a leukotriene receptor antagonist and antihistamine in the treatment of asthma patients.
References Nishimura, M. et al.: Kur. Med. J., 58, 9 (2011); Sanchis-Merino, M. et al.: Exp. Eye Res., 86, 791 (2008);Formula:C17H26N4O·2C4H4O4Color and Shape:NeatMolecular weight:534.56Emedastine difumarate
CAS:1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole difumarateFormula:C25H34N4O9Purity:98%Molecular weight:534.56
