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CAS 87616-84-0

:

(D-trp7,ala8,D-phe10)-A-melanocyte*stimulating ho

Description:
The substance known as (D-Trp7, Ala8, D-Phe10)-A-melanocyte-stimulating hormone (CAS 87616-84-0) is a synthetic analog of the naturally occurring melanocyte-stimulating hormone (MSH), which plays a crucial role in regulating pigmentation, appetite, and energy homeostasis. This peptide is characterized by its modified amino acid sequence, which includes D-amino acids at specific positions, enhancing its stability and bioactivity compared to the native hormone. The incorporation of D-Trp, Ala, and D-Phe contributes to its receptor binding affinity and biological activity, making it a valuable compound in research related to skin pigmentation and potential therapeutic applications. The structural modifications also help in reducing enzymatic degradation, thereby prolonging its action in biological systems. As a peptide, it is typically administered via injection and is of interest in studies related to dermatology and endocrinology. Its unique properties make it a subject of investigation for understanding the mechanisms of skin pigmentation and the regulation of appetite.
Formula:C46H56N12O6
InChI:InChI=1/C46H56N12O6/c1-27(54-44(62)39(20-29-23-51-35-15-7-5-13-32(29)35)57-43(61)34(48)22-31-25-50-26-53-31)42(60)56-40(21-30-24-52-36-16-8-6-14-33(30)36)46(64)58-38(19-28-11-3-2-4-12-28)45(63)55-37(41(49)59)17-9-10-18-47/h2-8,11-16,23-27,34,37-40,51-52H,9-10,17-22,47-48H2,1H3,(H2,49,59)(H,50,53)(H,54,62)(H,55,63)(H,56,60)(H,57,61)(H,58,64)/t27-,34-,37-,38?,39+,40-/m0/s1
Synonyms:
  • (D-Trp7,Ala8,D-Phe10)-.alpha.-MSH (6-11)
  • H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
  • Ghrp-6
  • L-histidyl-D-tryptophyl-L-alanyl-L-tryptophylphenylalanyl-L-lysinamide
  • Growth Hormone Releasing Peptide
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Found 8 products.
  • (D-Trp⁷,Ala⁸,D-Phe¹⁰)-α-MSH (6-11) amide

    CAS:
    In search of competitive α-MSH antagonists, the hexapeptide GHRP-6 has been recognized as a selective inhibitor of α-MSH activity in the frog skin bioassay. It is identical in sequence with a growth hormone-releasing peptide analog, (His¹,Lys⁶)-GHRP, which selectively releases GH in vitro and in a wide variety of species in vivo. GHRP-6 also acts as a functional antagonist of somatostatin in the somatotrope cells.
    Formula:C46H56N12O6
    Purity:98.3%
    Color and Shape:Light Yellow Powder
    Molecular weight:873.03

    Ref: 01-4008401

    5mg
    129.00€
    25mg
    493.00€
  • Hexapeptide-2

    CAS:
    Formula:C46H56N12O6
    Molecular weight:873.03

    Ref: 4Z-PH-097001

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide Acetate Salt

    Controlled Product
    CAS:
    Formula:C46H56N12O6·x(C2H4O2)
    Color and Shape:Neat
    Molecular weight:873.01 + x(60.05)

    Ref: TR-H456210

    1mg
    116.00€
  • H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2

    CAS:
    <p>H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 is a potent activator of the human growth hormone receptor, which leads to increased levels of insulin growth factor 1 (IGF1). H-His-D-Trp-Ala-Trp-D-Phe-Lys NH2 causes an increase in locomotor activity and somatotrophs. This peptide has been shown to be effective in treating metabolic disorders such as obesity and diabetes mellitus type 2. It also has antiviral properties that may be useful for the treatment of infectious diseases, such as HIV.</p>
    Formula:C46H56N12O6
    Purity:Min. 95%
    Molecular weight:873.04 g/mol

    Ref: 3D-PGH-3694-PI

    1mg
    135.00€
    5mg
    198.00€
  • Growth hormone releasing peptide

    CAS:
    <p>Growth hormone releasing peptide (GHRP) is a cyclase inhibitor that blocks the release of endogenous growth hormone. This peptide acts on both igf-i and somatotrophs, with receptor activity in the hypothalamus. GHRP can be used to increase body weight and control obesity. It has been shown to stimulate cell division and inhibit apoptosis in vitro. In vivo studies have shown that GHRP stimulates the proliferation of ester hydrochloride cells in the liver, heart, kidney, and brain. GHRP also has an anti-inflammatory effect on humans by reducing cytosolic Ca2+ levels.</p>
    Formula:C46H56N12O6
    Purity:Min. 95%
    Molecular weight:873.01 g/mol

    Ref: 3D-FG40484

    25mg
    863.00€
  • GHRP-6

    CAS:
    <p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>
    Formula:C46H56N12O6
    Molecular weight:873.01 g/mol

    Ref: 3D-PP50490

    2mg
    291.00€
    5mg
    410.00€
    10mg
    607.00€
    25mg
    863.00€
    50mg
    1,356.00€
  • Hexapeptide-2

    CAS:
    Formula:C50H64N12O6
    Purity:95%
    Color and Shape:Solid
    Molecular weight:929.1200

    Ref: IN-DA004I2C

    5mg
    Discontinued
    10mg
    Discontinued
    25mg
    Discontinued
    100mg
    Discontinued
    Discontinued product