CAS 877052-79-4

4-(3,5-Bis(trifluoromethyl)benzyl)-6-(2-fluorophenyl)-4,5-dihydropyrido[3,2-f][1,4]oxazepin-3(2H)-one

CAS: 877052-79-4

4-(3,5-Bis(trifluoromethyl)benzyl)-6-(2-fluorophenyl)-4,5-dihydropyrido[3,2-f][1,4]oxazepin-3(2H)-one

Formula: C₂₃H₁₅F₇N₂O₂

Purity: ≥98%

Molecular weight: 484.37

Ref: 54-PC1030239

GPBAR-A

CAS: 877052-79-4

GPBAR-A is a synthetic small-molecule agonist of GPBAR1, also known as TGR5, that activates this G protein–coupled bile acid receptor involved in energy homeostasis, glucose metabolism, and immune regulation, GPBAR-A is extensively studied for its therapeutic potential in metabolic disorders such as type 2 diabetes, obesity, and inflammation-related diseases.

Formula: C₂₃H₁₅F₇N₂O₂

Purity: 99.99%

Color and Shape: White Solid

Molecular weight: 484.37

Ref: TM-T22200

GPBAR-A

CAS: 877052-79-4

GPBAR-A is an active form of Glucose-dependent insulinotropic polypeptide (GIP) that has been shown to increase insulin sensitivity. GPBAR-A is a peptide hormone that belongs to the glucagon family and has been found to activate physiological responses in the pancreas, liver, and intestines. It is produced by pancreatic beta cells in response to glucose and increases insulin secretion from the pancreas. GPBAR-A also reduces hepatic steatosis in mice fed a high fat diet, which may be due to its ability to stimulate fatty acid oxidation by activating peroxisome proliferator-activated receptors (PPARs).

Formula: C₂₃H₁₅F₇N₂O₂

Purity: Min. 95%

Molecular weight: 484.37 g/mol

Ref: 3D-CKB05279