CAS 87726-17-8

Panipenem

Description:

Panipenem is a broad-spectrum beta-lactam antibiotic belonging to the carbapenem class, which is known for its effectiveness against a wide range of Gram-positive and Gram-negative bacteria. It is characterized by its ability to inhibit bacterial cell wall synthesis, leading to cell lysis and death. Panipenem is often used in combination with another agent, such as cilastatin, to prevent its degradation by renal dehydropeptidase I, thereby enhancing its therapeutic efficacy. The compound is typically administered intravenously and is indicated for serious infections, including those caused by multidrug-resistant organisms. Its stability against various beta-lactamases makes it a valuable option in treating infections that are resistant to other antibiotics. However, like other antibiotics, it may be associated with side effects, including gastrointestinal disturbances and potential allergic reactions. Due to its broad-spectrum activity, panipenem is often reserved for use in hospital settings where resistant infections are more prevalent.

Formula: C₁₅H₂₁N₃O₄S

InChI: InChI=1S/C15H21N3O4S/c1-7(19)12-10-5-11(13(15(21)22)18(10)14(12)20)23-9-3-4-17(6-9)8(2)16/h7,9-10,12,16,19H,3-6H2,1-2H3,(H,21,22)/t7-,9+,10-,12-/m1/s1

InChI key: InChIKey=TYMABNNERDVXID-DLYFRVTGSA-N

SMILES: [C@H](C)(O)[C@@]1([C@@]2(N(C(C(O)=O)=C(S[C@@H]3CN(C(C)=N)CC3)C2)C1=O)[H])[H]

Synonyms:

• (5R,6S)-3-({(3S)-1-[(1E)-ethanimidoyl]pyrrolidin-3-yl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[(3S)-1-(1-iminoethyl)-3-pyrrolidinyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-[[1-(1-iminoethyl)-3-pyrrolidinyl]thio]-7-oxo-, [5R-[3(S*),5α,6α(R*)]]-
• 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[(3S)-1-(1-iminoethyl)-3-pyrrolidinyl]thio]-7-oxo-, (5R,6S)-
• Cs 533
• Rs 533

(5R,6S)-6-((R)-1-Hydroxyethyl)-3-(((S)-1-(1-iminoethyl)pyrrolidin-3-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS: 87726-17-8

Formula: C₁₅H₂₁N₃O₄S

Color and Shape: Solid

Molecular weight: 339.4099

Ref: IN-DA004GBB

Panipenem

CAS: 87726-17-8

Ref: 7W-GA1410

Panipenem

CAS: 87726-17-8

Panipenem is a carbapenem antibiotic used in combination with betamipron.

Formula: C₁₅H₂₁N₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 339.41

Ref: TM-T20737

Panipenem

Controlled Product

CAS: 87726-17-8

Formula: C₁₅H₂₁N₃O₄S

Color and Shape: Neat

Molecular weight: 339.41

Ref: TR-P180000

Panipenem

CAS: 87726-17-8

Panipenem is a carbapenem antibiotic, which is a type of beta-lactam antibiotic derived from thienamycin. It functions by inhibiting penicillin-binding proteins (PBPs), which are essential for bacterial cell wall synthesis. This inhibition disrupts the cell wall construction, leading to cell lysis and death, thereby demonstrating strong bactericidal activity.

Formula: C₁₅H₂₁N₃O₄S

Purity: Min. 95%

Molecular weight: 339.41 g/mol

Ref: 3D-FP75030