CymitQuimica logo

CAS 87726-17-8

:

Panipenem

Description:
Panipenem is a broad-spectrum beta-lactam antibiotic belonging to the carbapenem class, which is known for its effectiveness against a wide range of Gram-positive and Gram-negative bacteria. It is characterized by its ability to inhibit bacterial cell wall synthesis, leading to cell lysis and death. Panipenem is often used in combination with another agent, such as cilastatin, to prevent its degradation by renal dehydropeptidase I, thereby enhancing its therapeutic efficacy. The compound is typically administered intravenously and is indicated for serious infections, including those caused by multidrug-resistant organisms. Its stability against various beta-lactamases makes it a valuable option in treating infections that are resistant to other antibiotics. However, like other antibiotics, it may be associated with side effects, including gastrointestinal disturbances and potential allergic reactions. Due to its broad-spectrum activity, panipenem is often reserved for use in hospital settings where resistant infections are more prevalent.
Formula:C15H21N3O4S
InChI:InChI=1S/C15H21N3O4S/c1-7(19)12-10-5-11(13(15(21)22)18(10)14(12)20)23-9-3-4-17(6-9)8(2)16/h7,9-10,12,16,19H,3-6H2,1-2H3,(H,21,22)/t7-,9+,10-,12-/m1/s1
InChI key:InChIKey=TYMABNNERDVXID-DLYFRVTGSA-N
SMILES:[C@H](C)(O)[C@@]1([C@@]2(N(C(C(O)=O)=C(S[C@@H]3CN(C(C)=N)CC3)C2)C1=O)[H])[H]
Synonyms:
  • (5R,6S)-3-({(3S)-1-[(1E)-ethanimidoyl]pyrrolidin-3-yl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[(3S)-1-(1-iminoethyl)-3-pyrrolidinyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-[[1-(1-iminoethyl)-3-pyrrolidinyl]thio]-7-oxo-, [5R-[3(S*),5α,6α(R*)]]-
  • 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[(3S)-1-(1-iminoethyl)-3-pyrrolidinyl]thio]-7-oxo-, (5R,6S)-
  • Cs 533
  • Rs 533
Found 5 products.