CAS 87741-77-3

Notoginsenoside R4

Description:

Notoginsenoside R4 is a saponin compound primarily derived from the roots of Panax notoginseng, a traditional medicinal plant known for its various health benefits. This compound is characterized by its complex glycosidic structure, which contributes to its biological activity. Notoginsenoside R4 exhibits anti-inflammatory, antioxidant, and neuroprotective properties, making it of interest in pharmacological research. It is often studied for its potential effects on cardiovascular health and its ability to enhance cognitive function. The compound is soluble in organic solvents and has limited solubility in water, which can influence its bioavailability and therapeutic applications. Additionally, Notoginsenoside R4 is recognized for its role in modulating various signaling pathways, thereby impacting cellular processes. Its safety profile and efficacy are subjects of ongoing research, particularly in the context of traditional medicine and modern therapeutic approaches. Overall, Notoginsenoside R4 represents a significant area of interest in natural product chemistry and pharmacology.

Formula: C₅₉H₁₀₀O₂₇

InChI: InChI=1S/C59H100O27/c1-24(2)10-9-14-59(8,86-53-48(76)43(71)40(68)31(83-53)23-79-51-46(74)42(70)39(67)30(82-51)22-78-50-45(73)36(64)27(63)21-77-50)25-11-16-58(7)35(25)26(62)18-33-56(5)15-13-34(55(3,4)32(56)12-17-57(33,58)6)84-54-49(44(72)38(66)29(20-61)81-54)85-52-47(75)41(69)37(65)28(19-60)80-52/h10,25-54,60-76H,9,11-23H2,1-8H3/t25-,26+,27+,28+,29+,30+,31+,32-,33+,34-,35-,36-,37+,38+,39+,40+,41-,42-,43-,44-,45+,46+,47+,48+,49+,50-,51+,52-,53-,54-,56-,57+,58+,59-/m0/s1

InChI key: InChIKey=IWDYQBDCEDNTDP-BHPIZNGBSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](CO)O4)CC3)[H])(C[C@@H](O)[C@]6([C@@]2(C)CC[C@@]6([C@@](O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO[C@H]9[C@H](O)[C@@H](O)[C@H](O)CO9)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)(CCC=C(C)C)C)[H])[H])[H]

Synonyms:

• Notoginsenoside R4
• β-D-Glucopyranoside, (3β,12β)-12-hydroxy-20-[(O-β-D-xylopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
• (3β,12β)-12-Hydroxy-20-[(O-β-D-xylopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

Notoginsenoside R4

CAS: 87741-77-3

Notoginsenoside R4

Molecular weight: 1240.65

Ref: 10-F558079

Notoginsenoside R4

CAS: 87741-77-3

Formula: C₅₉H₁₀₀O₂₇

Purity: 95%~99%

Molecular weight: 1241.42

Ref: BP-BP5263

Notoginsenoside R4 (Standard)

CAS: 87741-77-3

Notoginsenoside R4 (Standard) is a reference standard for research and analysis in studies involving Notoginsenoside R4. Notoginsenoside R4 is a ginsenoside obtainable from ginseng roots and participates in molecular docking interactions with core disease-related targets including STAT3, AKT1, HRAS, VEGFA, and CASP3, demonstrating favorable binding affinity. These docking results of Notoginsenoside R4, complemented by visualization analyses, highlight Notoginsenoside R4 as an important functional constituent of Panax notoginseng saponins (PNS) with mechanistic implications for anticancer and pro-apoptotic signaling regulation.

Formula: C₅₉H₁₀₀O₂₇

Molecular weight: 1241.409

Ref: TM-TMSM-2738

Notoginsenoside R4

CAS: 87741-77-3

Notoginsenoside R4, a ginsenoside from Panax notoginseng, binds STAT3, AKT1, VEGFA, and CASP3, demonstrating anticancer and pro-apoptotic signaling modulation.

Formula: C₅₉H₁₀₀O₂₇

Purity: 99.77%

Color and Shape: White Solid

Molecular weight: 1241.409

Ref: TM-TN6691

Notoginsenoside R4

CAS: 87741-77-3

Formula: C₅₉H₁₀₀O₂₇

Purity: 98%

Molecular weight: 1241.4091

Ref: IN-DA01OUOA

(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

CAS: 87741-77-3

Formula: C₅₉H₁₀₀O₂₇

Purity: 98%

Molecular weight: 1241.41

Ref: IN-DG02569159

Notoginsenoside R4

CAS: 87741-77-3

Formula: C₅₈H₉₈O₂₇

Molecular weight: 1227.4

Ref: BE-RMT14250

Notoginsenoside R4

CAS: 87741-77-3

Notoginsenoside R4 is a bioactive compound, which is a saponin extracted from the roots of Panax notoginseng. This herb, which is a member of the Araliaceae family, is renowned in traditional Chinese medicine for its wide range of pharmacological properties. Notoginsenoside R4 acts primarily by modulating various signaling pathways and demonstrating antioxidant, anti-inflammatory, and neuroprotective effects. It influences cellular mechanisms such as apoptosis and angiogenesis, which are critical in disease pathogenesis and treatment.

Formula: C₅₉H₁₀₀O₂₇

Purity: Min. 95%

Molecular weight: 1,241.4 g/mol

Ref: 3D-MDA74177