CAS 87764-47-4

4-Deoxy-4-Fluoro-D-Mannose

Description:

4-Deoxy-4-Fluoro-D-Mannose is a fluorinated monosaccharide derivative of mannose, characterized by the substitution of a fluorine atom at the 4-position of the sugar molecule. This modification can significantly influence its biochemical properties and interactions. The compound typically exists as a white to off-white solid and is soluble in polar solvents such as water and methanol, which is common for many sugars and their derivatives. Its molecular structure includes a six-membered pyranose ring, which is a common feature in carbohydrate chemistry. The presence of the fluorine atom can enhance the compound's stability and alter its reactivity, making it of interest in various fields, including medicinal chemistry and biochemistry. 4-Deoxy-4-Fluoro-D-Mannose may also exhibit unique biological activities, potentially serving as a tool for studying carbohydrate-protein interactions or as a precursor in the synthesis of more complex molecules. As with any chemical substance, proper handling and safety precautions should be observed due to potential reactivity and biological effects.

Formula: C₆H₁₁FO₅

InChI: InChI=1/C6H11FO5/c7-5(3(10)1-8)6(12)4(11)2-9/h2-6,8,10-12H,1H2/t3-,4-,5-,6-/m1/s1

InChI key: GCEGLMFBNPWYQO-KVTDHHQDSA-N

SMILES: C([C@H]([C@H]([C@@H]([C@@H](C=O)O)O)F)O)O

Synonyms:

• 4-Deoxy-4-fluoromannose
• D-Mannose, 4-deoxy-4-fluoro-
• 4-Deoxy-4-fluoro-D-mannose

4-Deoxy-4-fluoro-D-mannose

CAS: 87764-47-4

4-Deoxy-4-fluoro-D-mannose is a biochemical reagent utilized in glycobiology research. Glycobiology examines the structure, synthesis, biology, and evolution of sugars. This field encompasses aspects of carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan interactions, and the role of glycans in biological systems. It is closely linked to fundamental research, biomedicine, and biotechnology.

Formula: C₆H₁₁FO₅

Color and Shape: Solid

Molecular weight: 182.15

Ref: TM-TSW-00407

4-Deoxy-4-fluoro-D-mannose

CAS: 87764-47-4

4-Deoxy-4-fluoro-D-mannose

Formula: C₆H₁₁FO₅

Purity: ≥95%

Molecular weight: 182.147

Ref: 54-PC7313

4-Deoxy-4-fluoro-D-mannose

CAS: 87764-47-4

Molecular weight: 182.1

Ref: 7W-GC6508

4-Deoxy-4-fluoro-D-mannose

CAS: 87764-47-4

4-Deoxy-4-fluoro-D-mannose is a sugar that is an analog of 3-deoxy-3-fluoro-d-mannose. It is synthesized by the transfer of a 6-hydroxyl group from 6,6'-dideoxyadenosine to the C6 hydroxyl group of 3,6'-dihexadecylthio adenosine. 4,4'-Difluoro D-mannose is then obtained by hydrolysis and decarboxylation. This process can be catalyzed by enzyme catalysis with phosphofructokinase or hexokinase. 4,4'-Difluoro D mannose has been used in biochemical studies as an analog for 6,6'-dideoxydaunosine. It has also been used as a substrate for virus glycosylation and protein glycosylation in living cells. In addition, it has been shown to inhibit

Formula: C₆H₁₁FO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 182.15 g/mol

Ref: 3D-MD04717

4-Deoxy-4-fluoro-D-mannose

Controlled Product

CAS: 87764-47-4

Applications Shown to be metabolized in yeast. Also shown to interfere with the glycosylation of viral G-protein in vesicular-stomatitis-virus-infected BHK cells.
References Biochem. J., 209 (3), 677-685 (1983), J. Biol. Chem., 259, 1027-1030 (1984)

Formula: C₆H₁₁FO₅

Color and Shape: Neat

Molecular weight: 182.15

Ref: TR-D235300

D-Mannose,4-deoxy-4-fluoro-

CAS: 87764-47-4

Formula: C₆H₁₁FO₅

Molecular weight: 182.1469

Ref: IN-DA004FB8