CAS 877963-94-5

Formula: C16H19N3O2S

InChI: InChI=1S/C16H19N3O2S/c20-15(12-5-6-12)18-9-7-17(8-10-18)11-19-16(21)13-3-1-2-4-14(13)22-19/h1-4,12H,5-11H2

InChI key: YVBSNHLFRIVWFQ-UHFFFAOYSA-N

SMILES: C1CC1C(=O)N2CCN(CC2)CN3C(=O)C4=CC=CC=C4S3

LOC14

CAS: 877963-94-5

LOC14

Formula: C₁₆H₁₉N₃O₂S

Purity: 99.5%

Molecular weight: 317.41

Ref: 54-BUP06128

LOC14

CAS: 877963-94-5

Formula: C₁₆H₁₉N₃O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.4060

Ref: IN-DA01BCFP

LOC14

CAS: 877963-94-5

LOC14 to be the most potent PDI inhibitor reported to date( EC50 : 500 nM)

Formula: C₁₆H₁₉N₃O₂S

Purity: 99.62%

Color and Shape: Solid

Molecular weight: 317.41

Ref: TM-T5534

2-((4-(Cyclopropanecarbonyl)piperazin-1-yl)methyl)benzo[d]isothiazol-3(2H)-one

CAS: 877963-94-5

2-((4-(Cyclopropanecarbonyl)piperazin-1-yl)methyl)benzo[d]isothiazol-3(2H)-one

Formula: C₁₆H₁₉N₃O₂S

Purity: 98%

Molecular weight: 317.41

Ref: IN-DG00803168

2-[(4-cyclopropanecarbonylpiperazin-1-yl)methyl]-2,3-dihydro-1,2-benzothiazol-3-one

CAS: 877963-94-5

Purity: 98%

Molecular weight: 317.4100037

Ref: 10-F864095

LOC14

CAS: 877963-94-5

LOC14 is a peptide derived from the human immunodeficiency virus (HIV) that has been shown to have anticancer activity. It was found to be active against tumor cells, but not normal cells, in culture. LOC14 is neuroprotective and prevents the activation of microglia in response to an inflammatory insult. This peptide also modulates the production of pro-inflammatory cytokines by inhibiting the phosphorylation of NF-κB and by preventing the degradation of IκBα protein. LOC14 inhibits food poisoning caused by enterotoxigenic Escherichia coli (ETEC) and other bacterial pathogens. It also has anti-inflammatory effects against inflammatory diseases such as rheumatoid arthritis and colitis.
LOC14 inhibits HIV infectivity by binding to gp41, which is a major component of HIV's envelope on the surface of infected cells. This interaction prevents gp41 from interacting with CD4 receptors on uninfected cells, thus

Formula: C₁₆H₁₉N₃O₂S

Purity: Min. 95%

Molecular weight: 317.41 g/mol

Ref: 3D-CKB96394