CAS 878557-55-2

WRW4

CAS: 878557-55-2

Antagonist of formyl peptide receptor-like 1 (FPRL1) signalling. WRW4 inhibits WKYMVm binding to FPRL1 (IC₅₀ 0.23 mM) as well as the intracellular calcium release induced by WKYMVm, MMK-1, amyloid β42, and F peptide. The tryptophan-rich peptide also inhibits FPRL1-mediated signalling in human neutrophils and blocks chemotactic migration and superoxide generation by Aβ42. WRW4 inhibited the activation of FPRL2 by F2L, an FPRL2-selective endogenous agonist, resulting in the complete inhibition of intracellular calcium increase and chemotactic migration.

Formula: C₆₁H₆₅N₁₅O₆

Purity: 95.0%

Color and Shape: White Lyophilisate

Molecular weight: 1104.27

Ref: 01-4095537

878557-55-2H-Trp-Arg-Trp-Trp-Trp-Trp-NH2 trifluoroacetate salt

CAS: 878557-55-2

Formula: C₆₁H₆₅N₁₅O₆

Purity: 98%

Molecular weight: 1104.2657

Ref: IN-DA01E9O5

(S)-N-((S)-1-(((S)-1-(((S)-1-(((S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2

CAS: 878557-55-2

(S)-N-((S)-1-(((S)-1-(((S)-1-(((S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2

Purity: 98%

Molecular weight: 1104.29g/mol

Ref: 54-OR1063517

WRW4

CAS: 878557-55-2

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Formula: C₆₁H₆₅N₁₅O₆

Purity: Min. 95%

Molecular weight: 1,104.27 g/mol

Ref: 3D-FW110173