CAS 879062-90-5

Formula: C10H18N4O2

InChI: InChI=1S/C10H18N4O2/c1-10(2)8(15)14(9(16)12-10)7-13-5-3-11-4-6-13/h11H,3-7H2,1-2H3,(H,12,16)

InChI key: LJNMTXMGPGCHPD-UHFFFAOYSA-N

SMILES: CC1(C(=O)N(C(=O)N1)CN2CCNCC2)C

3-Piperazinylmethyl-5,5-dimethylhydantoin Dihydrochloride

Controlled Product

CAS: 879062-90-5

Applications 3-Piperazinylmethyl-5,5-dimethylhydantoin Dihydrochloride, is a derivative of 5,5-Dimethylhydantoin (D473300). 3-Piperazinylmethyl-5,5-dimethylhydantoin is also part of a group of small molecules that have the ability to reversibly inhibit Protein Arginine Deiminase (PAD4), which can potentially be used to treat inflammatory bowel disease and cancer.
References Chumanevich, A., et al.: Am. J. Physiol-Endoc. M., 300, G929 (2011); Wang, Y., et al.: J. Biol. Chem., 287, 25941 (2012); Wei, L., et al.: J. Med. Chem., 56, 1715 (2013)

Formula: C₁₀H₁₈N₄O₂•2HCl

Color and Shape: Neat

Molecular weight: 299.2

Ref: TR-D473640