CAS 88050-17-3

fmoc-L-4-hydroxyproline

Description:

Fmoc-L-4-hydroxyproline is a derivative of the amino acid proline, specifically modified with a fluorenylmethyloxycarbonyl (Fmoc) protecting group at the nitrogen atom. This compound is characterized by its ability to serve as a building block in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to the stability of the Fmoc group under basic conditions and its ease of removal under mild acidic conditions. The presence of the 4-hydroxy group on the proline ring introduces unique steric and electronic properties, which can influence the conformation and stability of peptides. Fmoc-L-4-hydroxyproline is often utilized in the synthesis of peptides that require specific structural features, such as those involved in biological recognition processes. Additionally, it is soluble in organic solvents, making it suitable for various synthetic applications. Its CAS number, 88050-17-3, is used for identification in chemical databases and regulatory contexts. Overall, Fmoc-L-4-hydroxyproline is a valuable compound in the field of peptide chemistry and drug development.

Formula: C₂₀H₁₉NO₅

InChI: InChI=1/C20H19NO5/c22-12-9-18(19(23)24)21(10-12)20(25)26-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,12,17-18,22H,9-11H2,(H,23,24)/t12-,18+/m1/s1

InChI key: GOUUPUICWUFXPM-XIKOKIGWSA-N

SMILES: C1[C@H](CN([C@@H]1C(=O)O)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)O

Synonyms:

• Fmoc-Hyp-OH
• N-Fmoc-trans-4-hydroxy-L-proline
• (4R)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-hydroxy-L-proline
• Fmoc-trans-4-hydroxy-L-proline
• Fmoc-L-Hydroxyproline
• (2S,4R)-N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
• FMOC-TRANS-4-HYP-OH
• RARECHEM EM WB 0137
• FMOC-HYP-OH (TRANS)
• FMOC-L-TRANS-4-HYDROXYPROLINE
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-TRANS-L-HYDROXYPROLINE
• FMOC-L-T-4-HYDROXYPROLINE
• (2S,4R)-N-ALPHA-(Y-FLUORENYLMETHOXYCARBONYL)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
• FMOC-HYDROXYPROLINE
• FMOC-L-HYP-OH
• FMOC-HYP-OH 99%MIN
• N-ALPHA-FMOC-L-TRANS-4-HYDROXYPROLINE
• N-FMOC-L-TRANS-4-HYDROXYPROLINE
• FMOC-L-4-HYDROXYPROLINE
• N-Fmoc-cis-4-hydroxy-D-proline

Fmoc-Hyp-OH

CAS: 88050-17-3

Formula: C₂₀H₁₉NO₅

Purity: >98.0%(HPLC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 353.37

Ref: 3B-F0899

trans-N-Fmoc-4-hydroxy-L-proline, 97%

CAS: 88050-17-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₀H₁₉NO₅

Purity: 97%

Color and Shape: White to beige to pale yellow, Solid

Molecular weight: 353.37

Ref: 02-H52740

Fmoc-Hyp-OH

CAS: 88050-17-3

Bachem ID: 4025531.

Formula: C₂₀H₁₉NO₅

Purity: 99.9%

Color and Shape: White Powder

Molecular weight: 353.38

Ref: 01-4025531

N-Fmoc-trans-4-hydroxy-L-proline

CAS: 88050-17-3

N-Fmoc-trans-4-hydroxy-L-proline

Formula: C₂₀H₁₉NO₅

Purity: 98%

Color and Shape: Light yellow Solid-Powder

Molecular weight: 353.36856

Ref: 54-OR307070

Fmoc-Hyp-OH

CAS: 88050-17-3

Formula: C₂₀H₁₉NO₅

Molecular weight: 353.37

Ref: 7W-GM5724

N-Fmoc-trans-4-Hydroxy-L-proline

CAS: 88050-17-3

Formula: C₂₀H₁₉NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 353.3686

Ref: IN-DA0034Y2

Fmoc-Hyp-OH

CAS: 88050-17-3

M03165 - Fmoc-Hyp-OH

Formula: C₂₀H₁₉NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 353.374

Ref: 10-M03165

Fmoc-Hyp-OH

CAS: 88050-17-3

Fmoc-Hyp-OH

Formula: C₂₀H₁₉NO₅

Purity: 98%

Molecular weight: 353.37

Ref: IN-DG35240

Fmoc-L-Hyp-OH

CAS: 88050-17-3

Fmoc-L-Hyp-OH is a protected proline analogue

Formula: C₂₀H₁₉NO₅

Purity: Min. 95%

Molecular weight: 353.37 g/mol

Ref: 3D-FF37442