CAS 880635-03-0

N-[(2S)-2-[[(1Z)-1-Methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]propanamide

Description:

The chemical substance N-[(2S)-2-[[(1Z)-1-Methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]propanamide, with CAS number 880635-03-0, is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as amides, ketones, and aromatic rings. This compound is likely to exhibit significant biological activity due to its structural features, which may interact with specific biological targets. The presence of trifluoromethyl and oxazole moieties suggests potential applications in medicinal chemistry, possibly as a pharmaceutical agent. Its stereochemistry, indicated by the (2S) configuration, may influence its pharmacokinetic properties and biological efficacy. Additionally, the compound's solubility, stability, and reactivity would depend on its molecular interactions, which are influenced by the various substituents present. Overall, this substance represents a class of compounds that may be of interest in drug discovery and development, particularly in the context of targeted therapies.

Formula: C₃₅H₃₆F₃N₃O₄

InChI: InChI=1S/C35H36F3N3O4/c1-4-33(43)39-22-29(40-23(2)20-32(42)26-12-14-28(15-13-26)35(36,37)38)21-25-10-16-30(17-11-25)44-19-18-31-24(3)45-34(41-31)27-8-6-5-7-9-27/h5-17,20,29,40H,4,18-19,21-22H2,1-3H3,(H,39,43)/b23-20-/t29-/m0/s1

InChI key: InChIKey=TYEFSRMOUXWTDN-DYQICHDWSA-N

SMILES: C(COC1=CC=C(C[C@H](N/C(=C\C(=O)C2=CC=C(C(F)(F)F)C=C2)/C)CNC(CC)=O)C=C1)C=3N=C(OC3C)C4=CC=CC=C4

Synonyms:

• GW 6471
• N-[(2S)-2-[[(1Z)-1-Methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]propanamide
• Propanamide, N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propenyl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]-
• Propanamide, N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]-

GW 6471

CAS: 880635-03-0

Formula: C₃₅H₃₆F₃N₃O₄

Purity: 99%

Color and Shape: Solid

Molecular weight: 619.6732

Ref: IN-DA00GX1C

GW6471

CAS: 880635-03-0

GW6471

Purity: ≥98%

Molecular weight: 619.67g/mol

Ref: 54-BUP08640

GW6471

CAS: 880635-03-0

Formula: C₃₅H₃₆F₃N₃O₄

Molecular weight: 619.67

Ref: 7W-GL6886

GW6471

CAS: 880635-03-0

GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.

Formula: C₃₅H₃₆F₃N₃O₄

Purity: 98.23% - 99.55%

Color and Shape: Solid

Molecular weight: 619.67

Ref: TM-T8486

GW 6471

Controlled Product

CAS: 880635-03-0

Formula: C₃₅H₃₆F₃N₃O₅

Color and Shape: Neat

Molecular weight: 635.673

Ref: TR-G931200

GW 6471

CAS: 880635-03-0

GW 6471 is a small molecule that inhibits the ATP-binding cassette transporter, which is involved in the uptake of glucose and other nutrients. GW 6471 has been shown to inhibit cancer cells by reducing their energy metabolism and inhibiting mitochondrial membrane potential. It also induces apoptosis of 3T3-L1 preadipocytes by activating signal pathways involving growth factor-β1 and PPARα. This drug also has anti-inflammatory properties in an experimental model using mouse heart tissue. GW 6471 is being developed as a treatment for bowel disease and congestive heart failure.

Formula: C₃₅H₃₆F₃N₃O₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 619.67 g/mol

Ref: 3D-BG179308