CAS 88247-69-2

Formula: C27H46O2

InChI: InChI=1S/C27H46O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1/i2D3,3D3

InChI key: INBGSXNNRGWLJU-KHKDDIDZSA-N

SMILES: [2H]C([2H])([2H])C(CCC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)(C([2H])([2H])[2H])O

25-hydroxy Cholesterol-d6

CAS: 88247-69-2

25-hydroxy Cholesterol-d6

Formula: C₂₇H₄₀D₆O₂

Purity: ≥99 atom% D

Molecular weight: 408.69

Ref: 54-DE3352

25-Hydroxycholesterol-D6

CAS: 88247-69-2

25-Hydroxycholesterol-D6 is the deuterium-labeled form of 25-Hydroxycholesterol. The latter is a cholesterol metabolite produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. This compound effectively and selectively inhibits IgA production in B cells, with an EC50 of approximately 65 nM.

Formula: C₂₇H₄₆O₂

Molecular weight: 408.69

Ref: TM-TMID-0684

25-Hydroxycholesterol-26,26,26,27,27,27-d6

CAS: 2140-46-7, 88247-69-2

Purity: 99 atom % D

Color and Shape: White Solid

Molecular weight: 408.70

Ref: 3U-D6774

25-Hydroxy Cholesterol-d6

Controlled Product

CAS: 88247-69-2

Applications 25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.
References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);

Formula: C₂₇D₆H₄₀O₂

Color and Shape: Neat

Molecular weight: 408.69

Ref: TR-H918032

25-Hydroxy-Cholesterol-d6

CAS: 88247-69-2

Formula: C₂₇H₄₀D₆O₂

Molecular weight: 408.70

Ref: 4Z-C-5354

25-Hydroxycholesterol-26,26,26,27,27,27-[d6]

CAS: 88247-69-2

Formula: C₂₇H₄₆O₂

Molecular weight: 408.7

Ref: BE-MD-2766

25-Hydroxy cholesterol-D6

Controlled Product

CAS: 88247-69-2

25-Hydroxy cholesterol-D6 is a pharmaceutical that is used in clinical settings. It can be used to measure the levels of oxysterols such as 25-hydroxycholesterol and 24,25-dihydroxycholesterol in blood plasma or cerebrospinal fluid. In addition, it can be used to detect the presence of oxysterols in red blood cells. This product has been shown to inhibit demyelination by preventing myelin sheath formation and also inhibits the production of an inflammatory molecule called tumor necrosis factor alpha (TNFα) in response to lipopolysaccharide (LPS).

Formula: C₂₇H₄₀D₆O₂

Purity: Min. 95%

Molecular weight: 408.69 g/mol

Ref: 3D-FH161167