CAS 88321-09-9: Loxistatin

Formula: C₁₇H₃₀N₂O₅

InChI: InChI=1S/C17H30N2O5/c1-6-23-17(22)14-13(24-14)16(21)19-12(9-11(4)5)15(20)18-8-7-10(2)3/h10-14H,6-9H2,1-5H3,(H,18,20)(H,19,21)/t12-,13-,14-/m0/s1

InChI key: InChIKey=SRVFFFJZQVENJC-IHRRRGAJSA-N

SMILES: O=C(OCC)C1OC1C(=O)NC(C(=O)NCCC(C)C)CC(C)C

Synonyms:

• 2-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, ethyl ester, (2S,3S)-
• Aloxistatin
• E 64c ethyl ester
• E-64d
• E64d
• E64d/pepstatin
• EST
• EST (pharmaceutical)
• Ep 453
• Loxistatin
• NSC 694281
• Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, ethyl ester, (2S,3S)-
• Oxiranecarboxylic acid, 3-[[[3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, ethyl ester, [2S-[2α,3β(R*)]]-
• Pepstatin E64d
• ethyl (2S,3S)-3-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}carbamoyl)oxirane-2-carboxylate
• ethyl (2S,3S)-3-[[1-(isopentylcarbamoyl)-3-methyl-butyl]carbamoyl]oxirane-2-carboxylate

L-trans-Epoxysuccinyl-Leu-3-methylbutylamide-ethyl ester

CAS: 88321-09-9

E64d (EST), a membrane permeable analog of E64c, was expected to be useful as an …

• Formula: C₁₇H₃₀N₂O₅
• Purity: > 99%
• Color and Shape: White
• Molecular weight: 342.44

E-64d

CAS: 88321-09-9

• Formula: C₁₇H₃₀N₂O₅
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 342.4305

E-64d

CAS: 88321-09-9

• Formula: C₁₇H₃₀N₂O₅
• Purity: 98.8% (hplc) (Typical Value in Batch COA)
• Color and Shape: Powder
• Molecular weight: 342.43g/mol

E-64d [for Biochemical Research]

CAS: 88321-09-9

• Formula: C₁₇H₃₀N₂O₅
• Purity: >95.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 342.44

Aloxistatin

CAS: 88321-09-9

Aloxistatin (E64d) inhibits cysteine proteases, blocks calpain in platelets, and prevents blood clotting.

• Formula: C₁₇H₃₀N₂O₅
• Purity: 98.12% - 99.47%
• Color and Shape: Solid
• Molecular weight: 342.43

E-64d protease inhibitor

CAS: 88321-09-9

• Formula: C₁₇H₃₀N₂O₅
• Purity: ≥ 95.0%
• Color and Shape: White powder
• Molecular weight: 342.43

L-TRANS-EPOXYSUCCINYL-LEU-3-METHYLBUTYLAMIDE-ETHYL ESTER

CAS: 88321-09-9

• Purity: 95.0%
• Molecular weight: 342.4360046386719

E-64d

CAS: 88321-09-9

Applications E-64d is an inhibitor of cathepsins B and L as well as a potential …

• Formula: C₁₇H₃₀N₂O₅
• Color and Shape: Neat
• Molecular weight: 342.43

(2S,3S)-trans-Epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester

CAS: 88321-09-9

Inhibitor of cathepsins

• Formula: C₁₇H₃₀N₂O₅
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 342.43 g/mol

E-64-d

CAS: 88321-09-9

E-64-d is a research tool that is used in cell biology, pharmacology, and biochemistry to …

• Formula: C₁₇H₃₀N₂O₅
• Purity: Min. 95%
• Molecular weight: 342.43 g/mol