CAS 883446-27-3
:Formula:C21H33ClF2N2O4
InChI:InChI=1S/C21H32F2N2O4.ClH/c1-12-20(29-11-21(3,4)5)28-10-18(24-12)19(27)17(25-13(2)26)8-14-6-15(22)9-16(23)7-14;/h6-7,9,12,17-20,24,27H,8,10-11H2,1-5H3,(H,25,26);1H/t12-,17-,18+,19-,20-;/m0./s1
InChI key:PJQGOUVTIKZTOU-QUQQOIKDSA-N
SMILES:C[C@H]1[C@@H](OC[C@@H](N1)[C@H]([C@H](CC2=CC(=CC(=C2)F)F)NC(=O)C)O)OCC(C)(C)C.Cl
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LY-2434074
CAS:LY-2434074 is a selective β-secretase (BACE) inhibitor with an IC50 value of less than 100 nM. It effectively inhibits the production of amyloid-beta proteins (Aβ40 and Aβ42) and is applicable in research on neurological disorders, including Alzheimer's disease.Formula:C21H33ClF2N2O4Molecular weight:450.95
