CAS 88495-63-0

Artesunate

Description:

Artesunate is a semi-synthetic derivative of artemisinin, which is extracted from the sweet wormwood plant, Artemisia annua. It is primarily used as an antimalarial medication, particularly effective against Plasmodium falciparum, the parasite responsible for the most severe form of malaria. Artesunate is known for its rapid action and is often administered intravenously or intramuscularly in severe cases. The compound has a molecular formula that includes carbon, hydrogen, and oxygen, reflecting its organic nature. Artesunate exhibits a unique mechanism of action, generating reactive oxygen species that damage the malaria parasite's cellular components. It is generally well-tolerated, though potential side effects can include gastrointestinal disturbances and allergic reactions. Artesunate is often used in combination therapies to enhance efficacy and reduce the risk of resistance development. Its stability and solubility in water make it suitable for various formulations, contributing to its widespread use in malaria treatment protocols globally.

Formula: C₁₉H₂₈O₈

InChI: InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16-,17-,18-,19-/m1/s1

InChI key: InChIKey=FIHJKUPKCHIPAT-AHIGJZGOSA-N

SMILES: C[C@@H]1[C@]2([C@]34[C@](O[C@H]1OC(CCC(O)=O)=O)(O[C@](C)(OO3)CC[C@]4([C@H](C)CC2)[H])[H])[H]

Synonyms:

• (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-ol hydrogen succinate
• 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, butanedioic acid deriv.
• 4-oxo-4-{[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy}butanoic acid
• 4-oxo-4-{[(5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]oxy}butanoic acid
• Arinate
• Armax 200
• Arsuamoon
• Arsumax
• Arteannuinum
• Arteannuinum succinate
• Artecan
• Artemisinin monosuccinate
• Artesunata
• ArtesunateC19H28O8
• Artesunic Acid
• Asumax
• Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester
• Butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester
• Butanedioic acid, mono(decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl) ester, [3R-(3α,5aβ,6β,8aβ,9α,10β,12β,12aR*)]-
• Butanedioic acid, mono[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester
• Cosunate
• Dihydroqinghasu hemsuccinate
• Gsunate Forte
• Hc 101B
• NSC 712571
• Plasmotrim
• Plasmotrin
• Qinghaozhi
• Saphnate
• Wr 256283
• Zysunate

Artesunate

CAS: 88495-63-0

Formula: C₁₉H₂₈O₈

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 384.43

Ref: 3B-A2191

ARTESUNATE RS

CAS: 88495-63-0

ARTESUNATE RS

Formula: C₁₉H₂₈O₈

Color and Shape: Powder

Molecular weight: 384.4208

Ref: 41-ICRS1409

Artesunate

CAS: 88495-63-0

Heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₁₉H₂₈O₈

Color and Shape: White Off-White Fine Crystalline Powder

Molecular weight: 384.17842

Ref: 45-1042850

Artesunate

CAS: 88495-63-0

Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.

Formula: C₁₉H₂₈O₈

Purity: 97.67% - 99.9%

Color and Shape: White Crystalline Powder

Molecular weight: 384.42

Ref: TM-T0433

Butanedioic acid,mono[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester

CAS: 88495-63-0

Formula: C₁₉H₂₈O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 384.4208

Ref: IN-DA00IF42

Artesunate

CAS: 88495-63-0

Artesunate

Purity: 99%

Molecular weight: 384.42g/mol

Ref: 54-OR1028903

Artesunate

CAS: 88495-63-0

Artesunate

Purity: ≥95%

Molecular weight: 384.42g/mol

Ref: 54-BUP17833

Artesunate

CAS: 88495-63-0

Formula: C₁₉H₂₈O₈

Molecular weight: 384.43

Ref: 4Z-A-107003

Artesunate

CAS: 88495-63-0

Formula: C₁₉H₂₈O₈

Color and Shape: Neat

Molecular weight: 384.42

Ref: 04-C10300550

Artesunate

CAS: 88495-63-0

Formula: C₁₉H₂₈O₈

Purity: 95%~99%

Molecular weight: 384.425

Ref: BP-BP0198

Artesunate

CAS: 88495-63-0

Color and Shape: Neat

Ref: 86-MM3253.00

Artesunate

CAS: 88495-63-0

Formula: C₁₉H₂₈O₈

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 384.42

Ref: 7W-GA7503

Artesunate

Controlled Product

CAS: 88495-63-0

Applications Derivative of Artemisinin. Antimalarial.
References Zhao, Y., et al.: J. Nat. Prod., 49, 139 (1986), Lin, A.J., et al.: J. Med. Chem., 30, 2147 (1987), Price, R. N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000),

Formula: C₁₉H₂₈O₈

Color and Shape: White To Off-White

Molecular weight: 384.42

Ref: TR-A777800

Artesunate

CAS: 88495-63-0

Prodrug of dihydroartemisin (DHA); antimalarial

Formula: C₁₉H₂₈O₈

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 384.42 g/mol

Ref: 3D-FA17994

Artesunate

CAS: 88495-63-0

Formula: C₁₉H₂₈O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 384.425

Ref: 10-F325208