CAS 885275-10-5

pyrazolo[1,5-a]pyridine-2-carbaldehyde

Description:

Pyrazolo[1,5-a]pyridine-2-carbaldehyde is a heterocyclic organic compound characterized by its unique bicyclic structure, which consists of a pyrazole ring fused to a pyridine ring. This compound features an aldehyde functional group at the 2-position of the pyrazole moiety, contributing to its reactivity and potential applications in organic synthesis. It typically appears as a solid or liquid, depending on the specific conditions, and is known for its role in medicinal chemistry, particularly in the development of pharmaceuticals due to its biological activity. The presence of both nitrogen atoms in the rings enhances its ability to participate in various chemical reactions, such as nucleophilic additions and condensation reactions. Pyrazolo[1,5-a]pyridine-2-carbaldehyde can be synthesized through various methods, often involving the reaction of appropriate precursors under controlled conditions. Its derivatives may exhibit diverse biological properties, making it a subject of interest in drug discovery and development. As with many organic compounds, handling should be done with care, following appropriate safety protocols.

Formula: C₈H₆N₂O

InChI: InChI=1/C8H6N2O/c11-6-7-5-8-3-1-2-4-10(8)9-7/h1-6H

InChI key: InChIKey=NIXHWFMRYWSRCN-UHFFFAOYSA-N

SMILES: C(=O)C=1C=C2N(N1)C=CC=C2

Synonyms:

• Pyrazolo[1,5-a]pyridine-2-carboxaldehyde
• 1H-pyrazolo[1,5-a]pyridine-2-carbaldehyde
• H-pyrazolo[1,5-a]pyridine-2-carbaldehyde

Pyrazolo[1,5-a]pyridine-2-carbaldehyde

CAS: 885275-10-5

Formula: C₈H₆N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 146.1460

Ref: IN-DA0046CG

Pyrazolo[1,5-a]pyridine-2-carbaldehyde

CAS: 885275-10-5

Pyrazolo[1,5-a]pyridine-2-carbaldehyde

Purity: 98%

Molecular weight: 146.15g/mol

Ref: 54-OR1035717

Pyrazolo[1,5-a]pyridine-2-carbaldehyde

CAS: 885275-10-5

Formula: C₈H₆N₂O

Purity: 98%

Molecular weight: 146.149

Ref: 10-F228097

Pyrazolo[1,5-a]pyridine-2-carbaldehyde

CAS: 885275-10-5

Pyrazolo[1,5-a]pyridine-2-carbaldehyde is a dopamine receptor ligand that binds to the D4 and D3 receptors. It has been shown to be an effective target compound for the treatment of depression, Parkinson's disease, and schizophrenia. Pyrazolo[1,5-a]pyridine-2-carbaldehyde has affinity constants with a Kd of 1.0 x 10^9 M and 2.2 x 10^9 M for the D4 and D3 receptors respectively. This compound also has high affinity constants with the amide moiety with a Kd of 1.7 x 10^8 M and 6.8 x 10^8 M for the d4 and d3 receptors respectively. The intermediates 3-(2,6-dimethoxyphenyl)-N-[(1S)-1-(aminocarbonyl)propyl]-4-(4-methylphenyl)piperid

Formula: C₈H₆N₂O

Purity: Min. 95%

Molecular weight: 146.15 g/mol

Ref: 3D-KKB27510