CAS 88637-37-0

Diphenhydramine citrate

Description:

Diphenhydramine citrate is a salt form of diphenhydramine, an antihistamine commonly used to relieve symptoms of allergy, hay fever, and the common cold. It is known for its sedative properties and is often utilized in over-the-counter sleep aids. The chemical structure of diphenhydramine citrate includes a diphenhydramine molecule combined with citric acid, which enhances its solubility and stability. This compound typically appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various formulations, including oral and injectable forms. Diphenhydramine acts primarily as an antagonist to the H1 histamine receptor, thereby reducing the effects of histamine in the body, which can alleviate symptoms such as itching, runny nose, and sneezing. Additionally, due to its sedative effects, it is sometimes used in the treatment of insomnia. However, it may cause side effects such as drowsiness, dry mouth, and dizziness, and caution is advised when used in conjunction with other central nervous system depressants.

Formula: C₂₃H₂₉NO₈

InChI: InChI=1/C17H21NO.C6H8O7/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-12,17H,13-14H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key: InChIKey=SPCKHVPPRJWQRZ-UHFFFAOYSA-N

SMILES: C(CC(O)=O)(CC(O)=O)(C(O)=O)O.C(OCCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

Synonyms:

• 2-(Benzhydryloxy)-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate
• 2-(diphenylmethoxy)-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
• Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• [2-(Diphenylmethoxy)Ethyl]Dimethylammonium Dihydrogen 2-Hydroxypropane-1,2,3-Tricarboxylate
• Diphenhydramine citrate
• Diphenhydramine Citrate (200 mg)
• 2-benzhydryloxy-N,N-dimethylethanamine,2-hydroxypropane-1,2,3-tricarboxylic acid
• Diphenhydramine citrate USP/EP/BP
• Benzhydramine citrate
• Diphenhydramine Citrate (125 mg)

Diphenhydramine Citrate

CAS: 88637-37-0

Aromatic drugs of amino-alcohols, other than those contg more than one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Formula: C₁₇H₂₁NO·C₆H₈O₇

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 447.18932

Ref: 45-1217909

Diphenhydramine Citrate

Controlled Product

CAS: 88637-37-0

Formula: C₁₇H₂₁NO·C₆H₈O₇

Color and Shape: Neat

Molecular weight: 447.48

Ref: TR-D486905

Diphenhydramine Citrate

CAS: 88637-37-0

Formula: C₁₇H₂₁NOC₆H₈O₇

Molecular weight: 255.4 : 192.1

Ref: ST-EA-CP-D23013