CAS 88678-31-3

Liranaftate

Description:

Liranaftate is an antifungal agent primarily used in the treatment of dermatophyte infections, such as athlete's foot and ringworm. It belongs to the class of compounds known as thiocarbamates, which function by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This disruption leads to increased membrane permeability and ultimately the death of the fungal cells. Liranaftate is typically formulated as a topical cream or powder, making it suitable for localized treatment. It is characterized by its relatively low toxicity in humans, which allows for safe application on the skin. The compound is generally well-tolerated, with minimal side effects, although some individuals may experience localized irritation. Its efficacy and safety profile make it a popular choice in dermatological practice for managing superficial fungal infections. As with any medication, it is important to follow the prescribed guidelines for use to ensure optimal results and minimize the risk of resistance development.

Formula: C₁₈H₂₀N₂O₂S

InChI: InChI=1S/C18H20N2O2S/c1-20(16-8-5-9-17(19-16)21-2)18(23)22-15-11-10-13-6-3-4-7-14(13)12-15/h5,8-12H,3-4,6-7H2,1-2H3

InChI key: InChIKey=VPHPQNGOVQYUMG-UHFFFAOYSA-N

SMILES: O(C(N(C)C=1N=C(OC)C=CC1)=S)C=2C=C3C(=CC2)CCCC3

Synonyms:

• Carbamothioic acid, (6-methoxy-2-pyridinyl)methyl-, O-(5,6,7,8-tetrahydro-2-naphthalenyl) ester
• Carbamothioic acid, N-(6-methoxy-2-pyridinyl)-N-methyl-, O-(5,6,7,8-tetrahydro-2-naphthalenyl) ester
• M 732
• N-(6-methoxy-2-Pyridyl)-N-methylthiocarbamic acid O-(5,6,7,8-tetrahydro-2-naphthyl)ester
• O-(5,6,7,8-Tetrahydro-2-naphthyl) N-(6-methoxy-2-pyridyl)-N-methylthiocarbamate
• O-(5,6,7,8-tetrahydronaphthalen-2-yl) (6-methoxypyridin-2-yl)methylcarbamothioate
• O-5,6,7,8-Tetrahydro-2-naphthyl 6-methoxy-2-pyridyl(methyl)thiocarbamate
• Piritetrate
• Zefnart
• Liranaftate

Liranaftate

CAS: 88678-31-3

Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity.

Formula: C₁₈H₂₀N₂O₂S

Purity: 98.96% - 99.92%

Color and Shape: White Crystalline Solid

Molecular weight: 328.43

Ref: TM-T1497

Liranaftate

CAS: 88678-31-3

Formula: C₁₈H₂₀N₂O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 328.4286

Ref: IN-DA0047GK

Liranaftate

CAS: 88678-31-3

Formula: C₁₈H₂₀N₂O₂S

Purity: ≥ 98.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 328.43

Ref: 7W-GP6552

Liranaftate

CAS: 88678-31-3

Liranaftate

Purity: ≥98%

Molecular weight: 328.43g/mol

Ref: 54-BUP15448

O-(5,6,7,8-Tetrahydronaphthalen-2-Yl) (6-Methoxypyridin-2-Yl)(Methyl)Carbamothioate

CAS: 88678-31-3

O-(5,6,7,8-Tetrahydronaphthalen-2-Yl) (6-Methoxypyridin-2-Yl)(Methyl)Carbamothioate

Purity: 98%

Molecular weight: 328.43g/mol

Ref: 54-OR1014512

Liranaftate

CAS: 88678-31-3

Formula: C₁₈H₂₀N₂O₂S

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 328.43

Ref: 3B-L0301

Liranaftate

CAS: 88678-31-3

Inhibitor of squalene epoxidase

Formula: C₁₈H₂₀N₂O₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 328.43 g/mol

Ref: 3D-FL24906