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CAS 88678-31-3

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Liranaftate

Description:
Liranaftate is an antifungal agent primarily used in the treatment of dermatophyte infections, such as athlete's foot and ringworm. It belongs to the class of compounds known as thiocarbamates, which function by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This disruption leads to increased membrane permeability and ultimately the death of the fungal cells. Liranaftate is typically formulated as a topical cream or powder, making it suitable for localized treatment. It is characterized by its relatively low toxicity in humans, which allows for safe application on the skin. The compound is generally well-tolerated, with minimal side effects, although some individuals may experience localized irritation. Its efficacy and safety profile make it a popular choice in dermatological practice for managing superficial fungal infections. As with any medication, it is important to follow the prescribed guidelines for use to ensure optimal results and minimize the risk of resistance development.
Formula:C18H20N2O2S
InChI:InChI=1S/C18H20N2O2S/c1-20(16-8-5-9-17(19-16)21-2)18(23)22-15-11-10-13-6-3-4-7-14(13)12-15/h5,8-12H,3-4,6-7H2,1-2H3
InChI key:InChIKey=VPHPQNGOVQYUMG-UHFFFAOYSA-N
SMILES:O(C(N(C)C=1N=C(OC)C=CC1)=S)C=2C=C3C(=CC2)CCCC3
Synonyms:
  • Carbamothioic acid, (6-methoxy-2-pyridinyl)methyl-, O-(5,6,7,8-tetrahydro-2-naphthalenyl) ester
  • Carbamothioic acid, N-(6-methoxy-2-pyridinyl)-N-methyl-, O-(5,6,7,8-tetrahydro-2-naphthalenyl) ester
  • M 732
  • N-(6-methoxy-2-Pyridyl)-N-methylthiocarbamic acid O-(5,6,7,8-tetrahydro-2-naphthyl)ester
  • O-(5,6,7,8-Tetrahydro-2-naphthyl) N-(6-methoxy-2-pyridyl)-N-methylthiocarbamate
  • O-(5,6,7,8-tetrahydronaphthalen-2-yl) (6-methoxypyridin-2-yl)methylcarbamothioate
  • O-5,6,7,8-Tetrahydro-2-naphthyl 6-methoxy-2-pyridyl(methyl)thiocarbamate
  • Piritetrate
  • Zefnart
  • Liranaftate
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