CAS 887144-94-7

1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one

Description:

1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one, with the CAS number 887144-94-7, is a chemical compound characterized by its unique structure that includes a benziodoxole moiety and a trifluoromethyl group. This compound is typically recognized for its role as a reagent in organic synthesis, particularly in the field of fluorination and oxidation reactions. The presence of the trifluoromethyl group enhances its reactivity and stability, making it a valuable intermediate in the synthesis of various fluorinated organic compounds. Additionally, the benziodoxole framework contributes to its electrophilic properties, allowing it to participate in diverse chemical transformations. The compound is generally handled with care due to its potential reactivity and the presence of fluorine, which can pose environmental and health risks. Overall, 1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one is an important tool in synthetic chemistry, particularly for researchers focused on developing new fluorinated materials and pharmaceuticals.

Formula: C₈H₄F₃IO₂

InChI: InChI=1S/C8H4F3IO2/c9-8(10,11)12-6-4-2-1-3-5(6)7(13)14-12/h1-4H

SMILES: c1ccc2c(c1)C(=O)OI2C(F)(F)F

Synonyms:

• 1-(Trifluoromethyl)-1,2-benziodoxol-3-(1H)-one(Togni's Reagent II)

1-Trifluoromethyl-1,2-benziodoxol-3(1H)-one (contains 60% Diatomaceous earth)

CAS: 887144-94-7

Formula: C₈H₄F₃IO₂

Color and Shape: White to Almost white powder to crystal

Molecular weight: 316.02

Ref: 3B-T3014

1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one

CAS: 887144-94-7

Formula: C₈H₄F₃IO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 316.0158

Ref: IN-DA0036A7

Togni Reagent II

Controlled Product

CAS: 887144-94-7

Stability Light Sensitive
Applications Used primarily as a reagent in trifluoromethylation reactions.
References Fantasia, S. et al.: J. Org. Chem., 75, 1779 (2010);

Formula: C₈H₄F₃IO₂

Color and Shape: Neat

Molecular weight: 316.02

Ref: TR-T529005

1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one

CAS: 887144-94-7

Purity: 97%

Molecular weight: 316.02

Ref: 10-F044423

1-(Trifluoromethyl)-1,2-benziodoxol-3(1h)-one

CAS: 887144-94-7

1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one is a deuterated analog of the phenoxy radical. It has been shown to be a potent inhibitor of the apical radiation-induced chain reactions in mitochondria and chloroplasts. The deuterium isotope effect makes 1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one more reactive than its non-deuterated counterpart. This increased reactivity leads to an increase in biological properties, such as toxicity studies and reaction mechanism. This drug also has modulating effects on sulfonic acids, which are important for many biological reactions.

Formula: C₈H₄F₃IO₂

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 316.02 g/mol

Ref: 3D-FT30314