CAS 889665-86-5

Formula: C20H18ClNO4

InChI: InChI=1S/C20H18NO4.ClH/c1-22-18-8-13-5-6-21-10-15-12(3-4-17-20(15)25-11-24-17)7-16(21)14(13)9-19(18)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1

InChI key: DGRBIBRPLDAHJH-UHFFFAOYSA-M

SMILES: COC1=C(C=C2C(=C1)CC[N+]3=C2C=C4C=CC5=C(C4=C3)OCO5)OC.[Cl-]

Epiberberine chloride

CAS: 889665-86-5

Epiberberine chloride

Formula: C₂₀H₁₈ClNO₄

Purity: 99.5%

Molecular weight: 371.81

Ref: 54-BUP04857

Epiberberine chloride

CAS: 889665-86-5

Formula: C₂₀H₁₈ClNO₄

Purity: 95%~99%

Molecular weight: 371.817

Ref: BP-BP6176

8,9-Dimethoxy-11,12-dihydro-[1,3]dioxolo[4,5-h]isoquinolino[2,1-b]isoquinolin-13-ium chloride

CAS: 889665-86-5

Formula: C₂₀H₁₈ClNO₄

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 371.8142

Ref: IN-DA01CC6J

Epiberberine chloride

CAS: 889665-86-5

Epiberberine chloride, a natural pro-berberine from Coptis chinensis Franch. is an AChE, BChE, and BACE1 inhibitor.

Formula: C₂₀H₁₈ClNO₄

Purity: 99.97%

Color and Shape: Orange Solid

Molecular weight: 371.814

Ref: TM-T8306

Epiberberine Chloride

CAS: 889665-86-5

Applications Epiberberine Chloride, is a natural bioactive alkaloid, an isomer of Berberine (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells.
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999); Liu, X. et al.: J. Pharm. Biomed. Anal., 98, 463 (2014);

Formula: C₂₀H₁₈NO₄·Cl

Color and Shape: Neat

Molecular weight: 371.81

Ref: TR-E578300

Epiberberine chloride

CAS: 889665-86-5

Epiberberine chloride is an alkaloid derivative, which is a compound derived from the protoberberine group. This product is primarily sourced from various plants, especially those belonging to the Berberidaceae family. The mode of action of epiberberine chloride involves modulating metabolic pathways, primarily influencing glucose and lipid metabolism. It achieves this by targeting specific enzymes and signaling molecules involved in these pathways, thereby altering cellular processes related to energy homeostasis.

Formula: C₂₀H₁₈ClNO₄

Purity: Min. 95%

Molecular weight: 371.81 g/mol

Ref: 3D-PKB66586