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CAS 89-57-6

:

5-Aminosalicylic acid

Description:
5-Aminosalicylic acid (5-ASA), with the CAS number 89-57-6, is an organic compound that belongs to the class of salicylates. It is characterized by the presence of both an amino group (-NH2) and a carboxylic acid group (-COOH) attached to a benzene ring, specifically at the 5 and 2 positions, respectively. This compound is a white to off-white crystalline powder that is soluble in water and exhibits weak acidity. 5-ASA is primarily known for its role as a therapeutic agent in the treatment of inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, due to its anti-inflammatory properties. It functions by inhibiting the production of inflammatory mediators and promoting mucosal healing. Additionally, 5-ASA can undergo various chemical reactions, including acetylation and esterification, which can modify its pharmacological properties. Its safety profile is generally favorable, although side effects may occur in some patients. Overall, 5-aminosalicylic acid is a significant compound in both medicinal chemistry and therapeutic applications.
Formula:C7H7NO3
InChI:InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)
InChI key:InChIKey=KBOPZPXVLCULAV-UHFFFAOYSA-N
SMILES:C(O)(=O)C1=C(O)C=CC(N)=C1
Synonyms:
  • 2-Hydroxy-5-aminobenzoic acid
  • 3-Carboxy-4-hydroxyaniline
  • 5-Amino Saliclic Acid
  • 5-Amino salicylic Acid
  • 5-Amino salicylic acidl
  • 5-Amino-2-Hydroxybenzoate
  • 5-Amino-2-hydroxybenzoic acid
  • 5-Aminosalicylsaeure
  • 5-Aminosalicylsaure
  • 5-Asa
  • See more synonyms
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