CAS 890842-28-1

GSK650394

Description:

GSK650394 is a small molecule compound that acts as a selective inhibitor of the protein kinase SGK1 (serum/glucocorticoid-regulated kinase 1). It is primarily studied for its potential therapeutic applications in various diseases, including cancer and metabolic disorders. The compound exhibits a high degree of specificity for SGK1, which is important for minimizing off-target effects and enhancing its efficacy in biological systems. GSK650394 is characterized by its ability to modulate cellular signaling pathways, particularly those involved in cell survival, proliferation, and metabolism. Its chemical structure includes specific functional groups that contribute to its binding affinity and inhibitory activity against SGK1. In research settings, GSK650394 is utilized to elucidate the role of SGK1 in cellular processes and to explore its potential as a drug candidate. As with many experimental compounds, further studies are necessary to fully understand its pharmacokinetics, pharmacodynamics, and safety profile in clinical applications.

Formula: C₂₅H₂₂N₂O₂

Synonyms:

• SGK inhibitor GS650394
• GSK650394 (Free base)
• Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-
• CS-1142
• GSK 650394
• 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid

GSK 650394

CAS: 890842-28-1

Formula: C₂₅H₂₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 382.4544

Ref: IN-DA00408H

GSK 650394

CAS: 890842-28-1

GSK 650394

Formula: C₂₅H₂₂N₂O₂

Purity: ≥95%

Molecular weight: 382.45

Ref: 54-BUP15193

GSK 650394

CAS: 890842-28-1

GSK 650394 is an inhibitor of serum- and glucocorticoid-regulated kinases (SGK). GSK 650394 has antitumor activity. Cost-effective and quality-assured.

Formula: C₂₅H₂₂N₂O₂

Purity: 97.46% - >99.99%

Color and Shape: White Solid

Molecular weight: 382.45

Ref: TM-T2622

GSK 650394

CAS: 890842-28-1

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid

Formula: C₂₅H₂₂N₂O₂

Purity: 99%

Molecular weight: 382.45

Ref: IN-DG299943

GSK 650394

CAS: 890842-28-1

Formula: C₂₅H₂₂N₂O₂

Molecular weight: 382.46

Ref: 4Z-K-031089

GSK 650394

CAS: 890842-28-1

Ref: BE-RMCK020087

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoic acid

CAS: 890842-28-1

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-benzoic acid (CPP) is a phenolic derivative that inhibits the activity of the cholesterol ester transfer protein (CETP). It has been shown to inhibit viral replication and to protect against lipid peroxidation in fetal bovine serum. CPP has also been shown to inhibit the expression of certain genes in cells, and it has been found to be stable in pharmaceutical dosage formulations. CPP is active against many Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae. This compound also displays anti-inflammatory properties.

Formula: C₂₅H₂₂N₂O₂

Purity: Min. 95%

Molecular weight: 382.46 g/mol

Ref: 3D-QKB84228

2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid

CAS: 890842-28-1

Formula: C₂₅H₂₂N₂O₂

Purity: 99%

Molecular weight: 382.463

Ref: 10-F511345