CAS 893772-67-3

Formula: C12H7F3N4O2

InChI: InChI=1S/C12H7F3N4O2/c1-19-7-3-2-5(12(13,14)15)4-6(7)16-8-9(19)17-11(21)18-10(8)20/h2-4H,1H3,(H,18,20,21)

InChI key: KCDITQBGZLRTBX-UHFFFAOYSA-N

SMILES: CN1C2=C(C=C(C=C2)C(F)(F)F)N=C3C1=NC(=O)NC3=O

10-Methyl-7-(trifluoromethyl)benzo[g]pteridine-2,4(3h,10h)-dione

CAS: 893772-67-3

10-Methyl-7-(trifluoromethyl)benzo[g]pteridine-2,4(3h,10h)-dione

Formula: C₁₂H₇F₃N₄O₂

Purity: 97%

Molecular weight: 296.2

Ref: 54-PC1027945

10-methyl-7-(trifluoromethyl)benzo[g]pteridine-2,4(3H,10H)-dione

CAS: 893772-67-3

Formula: C₁₂H₇F₃N₄O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 296.2048

Ref: IN-DA00JH64

PLK1-IN-9

CAS: 893772-67-3

PLK1-IN-9 (Compound M2), a polo-like kinase 1 (PLK1) inhibitor, targets the PLK proteins modified with peptides 1010pT, cdc25c, and PBIP, exhibiting IC₅₀ values of 1.6, 0.8, and 1.4 μM, respectively. This compound effectively inhibits the proliferation of various cancer cell lines including HeLa, HL60, SNU387/499, and HepG2, demonstrating cytotoxic effects and inducing apoptosis. Additionally, PLK1-IN-9 has been shown to suppress tumor growth in a HepG2 xenograft mouse model.

Formula: C₁₂H₇F₃N₄O₂

Molecular weight: 296.2048

Ref: TM-T87975

10-Methyl-7-(trifluoromethyl)benzo[g]pteridine-2,4(3H,10H)-dione

Controlled Product

CAS: 893772-67-3

Formula: C₁₂H₇F₃N₄O₂

Color and Shape: Neat

Molecular weight: 296.205

Ref: TR-M130640