CAS 89430-38-6

(D-trp-7,9,10)-substance P

Formula: C₇₉H₁₀₅N₂₁O₁₃S

InChI: InChI=1S/C79H105N21O13S/c1-114-37-32-56(68(84)103)91-72(107)61(39-46-42-88-53-22-8-5-18-49(46)53)98-74(109)63(41-48-44-90-55-24-10-7-20-51(48)55)97-71(106)60(38-45-16-3-2-4-17-45)95-73(108)62(40-47-43-89-54-23-9-6-19-50(47)54)96-70(105)57(28-30-66(82)101)92-69(104)58(29-31-67(83)102)93-75(110)65-27-15-36-100(65)78(113)59(25-11-12-33-80)94-76(111)64-26-14-35-99(64)77(112)52(81)21-13-34-87-79(85)86/h2-10,16-20,22-24,42-44,52,56-65,88-90H,11-15,21,25-41,80-81H2,1H3,(H2,82,101)(H2,83,102)(H2,84,103)(H,91,107)(H,92,104)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,106)(H,98,109)(H4,85,86,87)/t52-,56-,57-,58-,59-,60-,61+,62+,63+,64-,65-/m0/s1

InChI key: ZDXXOQXJCDHSRG-GGDSLUOHSA-N

SMILES: CSCC[C@@H](C(=O)N)NC(=O)[C@@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@@H](CC6=CNC7=CC=CC=C76)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H]8CCCN8C(=O)[C@H](CCCCN)NC(=O)[C@@H]9CCCN9C(=O)[C@H](CCCNC(=N)N)N

GP ANTAGONIST-2A

CAS: 89430-38-6

GP ANTAGONIST-2A

Formula: C₇₉H₁₀₅N₂₁O₁₃S

Purity: ≥98%

Molecular weight: 1588.88

Ref: 54-OR1113295

[D-Trp7,9,10]-Substance P

CAS: 89430-38-6

Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.

Formula: C₇₉H₁₀₅N₂₁O₁₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 1588.89

Ref: TM-TP1932

GP ANTAGONIST-2A

CAS: 89430-38-6

Formula: C₇₉H₁₀₅N₂₁O₁₃S

Purity: 98%

Molecular weight: 1588.8769

Ref: IN-DA00GRTU

[D-Trp7,9,10]-Substance P

CAS: 89430-38-6

Substance P is a neuropeptide that functions as a neurotransmitter and neuromodulator. It has been shown to inhibit inflammatory mediator release and regulate immune responses. Substance P regulates the functioning of the central nervous system by acting on various types of receptors, including heterotrimeric G protein-coupled receptors, which are composed of alpha-, beta-, and gamma-subunits. This peptide also inhibits the production of proinflammatory cytokines in response to bacterial lipopolysaccharides (LPS). In addition, Substance P is involved in the regulation of retromer function. The administration of Substance P modulates the activity of protein kinases and alters cannabinoid signaling pathways.

Formula: C₇₉H₁₀₅N₂₁O₁₃S

Purity: Min. 95%

Molecular weight: 1,588.9 g/mol

Ref: 3D-PDA43038