CAS 896466-04-9

1-cyclopropyl-3-[3-[5-(morpholinomethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]urea

Description:

1-Cyclopropyl-3-[3-[5-(morpholinomethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]urea, with CAS number 896466-04-9, is a synthetic organic compound characterized by its complex structure, which includes a cyclopropyl group, a benzimidazole moiety, and a pyrazole ring. This compound is typically classified as a urea derivative, which suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The presence of the morpholinomethyl group indicates that it may exhibit specific biological activities, possibly related to its interaction with biological targets. The structural features contribute to its solubility and stability, which are important for its efficacy in biological systems. Additionally, compounds of this nature often undergo various forms of chemical analysis to determine their purity, stability, and potential reactivity. Overall, the unique combination of functional groups in this compound may lead to interesting pharmacological properties, making it a subject of interest in drug discovery and development.

Formula: C₁₉H₂₃N₇O₂

InChI: InChI=1/C19H23N7O2/c27-19(21-13-2-3-13)24-16-10-20-25-17(16)18-22-14-4-1-12(9-15(14)23-18)11-26-5-7-28-8-6-26/h1,4,9-10,13H,2-3,5-8,11H2,(H,20,25)(H,22,23)(H2,21,24,27)

SMILES: c1cc2c(cc1CN1CCOCC1)nc(c1c(c[nH]n1)NC(=NC1CC1)O)[nH]2

Synonyms:

• At-9283

1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea

CAS: 896466-04-9

Formula: C₁₉H₂₃N₇O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 381.4316

Ref: IN-DA003699

AT9283

CAS: 896466-04-9

AT9283

Purity: ≥98%

Molecular weight: 381.43g/mol

Ref: 54-BUP03900

AT9283

CAS: 896466-04-9

Ref: 7W-GW8696

AT9283

CAS: 896466-04-9

AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).

Formula: C₁₉H₂₃N₇O₂

Purity: 99.83% - 99.98%

Color and Shape: Solid

Molecular weight: 381.43

Ref: TM-T3068

1-Cyclopropyl-3-(3-(5-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea

CAS: 896466-04-9

Formula: C₁₉H₂₃N₇O₂

Purity: 98%

Molecular weight: 381.44

Ref: 10-F230843

AT-9283

CAS: 896466-04-9

Applications AT-9283 is a potent AuroraA/AuroraB and multi-kinase inhibitor. AT-9283 has shown to inhibit growth and survival of multiple solid tumor cell lines and is efficacious in mouse xenograft models. It is a COVID19-related research product.
References Curry, J., et. al.: Cell Cycle, 8, 1921 (2009)

Formula: C₁₉H₂₃N₇O₂

Color and Shape: Neat

Molecular weight: 381.43

Ref: TR-A790300